Formoterol Fumarate is a Medicine belongs to Sympathomimetics used in asthma group whose information about Brand can be referenced from   Book : Martindale    Page : 1236   Edition : 37,    Page :   Edition : ,

  ►   Brandname : Foratec,Atimos Modulite,Foradil,Oxis,Atock,Forair,Foracort,Budetrol,Formoflo ,Formoflo Mdi

  ►  Strength : inhalant powder with 12  mcg, Inhalation Solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 355   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : inhalation,
Reference :-   Book : Martindale    Page : 1236   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Chronic obstructive pulmonary disease inhalation 1) A usual dose from inhalation capsules is formoterol fumarate 12 micrograms twice daily. 2) Metered doses from a dry powder inhaler, expressed as the amount delivered into the mouthpiece, are 12 micrograms once or twice daily while those from an aerosol inhaler are 12 micrograms twice daily. Maximum dose is 24 micrograms inhaled as a single dose. 3) Formoterol fumarate may also be inhaled via a nebuliser in a dose of 20 micrograms twice daily.
2 Asthma inhalation How the dose is expressed may depend on the formulation given as follows; 1) A usual dose is 12 micrograms of formoterol fumarate twice daily from 1 inhalational capsule. 2) Metered doses from a dry powder inhaler may be expressed as the amount delivered into the mouthpiece (multiples of 6 micrograms per inhalation) or the amount delivered from the mouthpiece (corresponding to multiples of 4.5 micrograms per inhalation). Usual doses, expressed as the amount delivered into the mouthpiece, are 6 or 12 micrograms once or twice daily, increased if necessary in severe disease to 24 micrograms twice daily. 3) Metered doses from an aerosol inhaler may also be expressed as the amount delivered into the mouthpiece (12 micrograms per inhalation) or the amount delivered from the mouthpiece (corresponding to 10.1 micrograms per inhalation). Usual doses are 1 or 2 inhalations twice daily.

Ref :-  Book : Martindale    Page : 1209,1210   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Asthma or Chronic obstructive pulmonary disease
2 Asthma or Chronic obstructive pulmonary disease 6 Year over 6 Year inhalation

Ref :- Book : Martindale    Page : 1210   Edition : 38,
►  Side Effect : significantly less cardiac effects due to beta2-receptor selectivity, less palpitations, less tachyarrhythmia, headache, Dizziness, tremor, Restlessness,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 834   Edition : 3, Martindale    Page : 1246   Edition : 37,

►  Drug Interaction : Drug interaction of Formoterol Fumarate is with Corticosteroids, Diuretics, Xanthines,  NA

  ►    Mechanism of Drug Drug Interaction :  Use of Formoterol Fumarate and other beta2 agonists with corticosteroids, diuretics, or xanthines increases the risk of hypokalaemia, and monitoring of potassium concentrations is recommended in severe asthma, where such combination therapy is common.,
Ref :-   Book : Martindale    Page : 1210,1223   Edition : 38,


►  Contraindication : should not be used in patients who are not also receiving an inhaled corticosteroid, treatment of acute bronchospasm,
Ref :-   Book : Martindale    Page : 1210   Edition : 38,
  ►  Mechanism of Action :   Formoterol is a direct-acting sympathomimetic with mainly beta-adrenoceptor stimulant activity specific to beta2 receptors (a beta2 agonist). It has properties similar to those of salbutamol.,
Ref :-   Book : Martindale    Page : 1209   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1236   Edition : 37,


►    Plasma Half-life :
  Min value :-   10 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 1236   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,