Fulvestrant is a Medicine belongs to Antineoplastic group whose information about Brand can be referenced from   Book : Martindale    Page : 800   Edition : 38,

  ►   Brandname : Faslodex

  ►  Strength : Injection with 50  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 740   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM,
Reference :-   Book : Martindale    Page : 800   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Treatment of oestrogen-receptor positive, locally advanced or metastatic breast cancer in postmenopausal women IM 500 mg Injection The drug is given when disease has relapsed or progressed during or after treatment with anti-oestrogens. It is given in the above mentioned dose in every 2 weeks for the first 3 doses, then every month thereafter. Half the dose (250 mg) is injected into each buttock concurrently.

Ref :-  Book : Martindale    Page : 800   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Most common adverse effects are, Gastrointestinal disturbances, musculoskeletal and abdominal pain, Cough, hot flashes, headache, asthenia, Increase in liver enzyme values, other common adverse effects include, Rashes, urinary-tract infections, thromboembolic complications, injection-site reactions have been reporetd, angioedema, Urticaria, ,
Ref :-   Book : Martindale    Page : 800   Edition : 38,

►  Drug Interaction : Drug interaction of Fulvestrant is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Severe hepatic impairment,
Ref :-   Book : Martindale    Page : 796   Edition : 37,
  ►  Mechanism of Action :   Fulvestrant is an oestrogen antagonist that downregulates the oestrogen receptor and is used for the treatment of oestrogen-receptor positive, locally advanced or metastatic breast cancer in postmenopausal women.,
Ref :-   Book : Martindale    Page : 800   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Faecal,
Ref :-   Book : Martindale    Page : 800   Edition : 38,


►    Plasma Half-life :
  Min value :-   40 to 50 days,    Max value :-   NA
Ref :-   Book : Martindale    Page : 800   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   after about 7 days,    Max value :-   NA
Ref :-   Book : Martindale    Page : 800   Edition : 38,