Furazolidone is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 934   Edition : 38  

  ►   Brandname : Furoxone
  ►  Strength : Oral Suspension with .  Tablet with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 934   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 933   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Treatment of giardiasis or cholera Oral 100 mg Tablet q.i.d. It is usually given for 2 to 5 days, but may be given for up to 7 days in some patients, or for up to 10 days for giardiasis.

Ref :-  Book : Martindale    Page : 933   Edition : 38  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Treatment of girardiasis, cholera, and other diarrhoeal diseases caused by susceptible organisms Oral 1.25 1.5 mg/kg Suspension q.i.d.

Ref :- Book : Martindale    Page : 933   Edition : 38  
►  Side Effect : Most common adverse effects are, Nausea, Vomiting, And, Dizziness, Drowsiness, Headache, General malaise, Rashes, Angioedema, Instances of acute pulmonary reactions, similar to those seen with the structurally related drug nitrofurantoin, and of hepatotoxicity, Haemolytic anaemia in patients with G6PD deficiency, Darkening of the urine
Ref :-   Book : Martindale    Page : 934   Edition : 38.      Page :    Edition : .  

►  Drug Interaction : Drug interaction of Furazolidone is with Alcohol, , , ,  Amitriptyline , Omeprazole
Ref :-   Book : Martindale    Page : 934   Edition : 38.  

  ►    Mechanism of Drug Drug Interaction :  A disulfiram-like reaction has been reported in patients taking alcohol while on furazolidone therapy; alcohol should be avoided during, and for a short period after, treatment with furazolidone. A metabolite of Furazolidone is an MAOI and the cautions advised for these drugs regarding use with other drugs, especially indirect-acting sympathomimetic amines, and the consumption of food and drink containing tyramine, should be observed. However, there appear to be no reports of hypertensive crises in patients receiving furazolidone and it has been suggested that, since furazolidone inhibits monoamine oxidase gradually over several days, the risks are small if treatment is limited to a 5-day course. Toxic psychosis has been reported in a patient receiving furazolidone and amitriptyline. Omeprazole modestly decreases serum concentrations of furazolidone; other proton pump inhibitors could interact similarly.
Ref :-   Book : Martindale    Page : 934   Edition : 38.  

►  Contraindication : Infants under 1 month of age
Ref :-   Book : Martindale    Page : 934   Edition : 38.  
  ►  Mechanism of Action :   Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It is bactericidal and appears to act by interfering with bacterial enzyme systems.
Ref :-   Book : Martindale    Page : 933   Edition : 38.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA

DIETARY Substance Interactions

​   ► This Medicine interact with :- NA

ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Metabolised in the intestine
Ref :-   Book : Martindale    Page : 934   Edition : 38.  

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA