Glycopyrrolate/Glycopyrronium Bromide is a Medicine belongs to Antimuscarinic Anticholinergic group whose information about Brand can be referenced from   Book : Martindale    Page : 2520   Edition : 38,

  ►   Brandname : Robinul; Glycate; Cuvposa; Glyco-P

  ►  Strength : Tablet with 1  mg, Tablet with 2  mg, Injection with 0.2  mg/ml, Oral solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 127   Edition : 12, Martindale    Page : 2520   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV, IM,
Reference :-   Book : Martindale    Page : 2519   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Given as a premedicant before general anaesthesia IM or IV 200 400 Microgram Injection Before the induction of anaesthesia.

Ref :-  Book : Martindale    Page : 2519   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Given as a premedicant before general anaesthesia IM or IV 5 micrograms/kg Injection
2 Given as a premedicant before general anaesthesia 1 Month Over 1 Month IM or IV 4 8 micrograms/kg Injection

Ref :- Book : Martindale    Page : 2519   Edition : 38,
►  Side Effect : cardiac arrhythmia, Malignant hyperthermia, anaphylaxis, constipation, seizure, Xerostomia, urinary retention, decreased sweating,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 130   Edition : 3,

►  Drug Interaction : Drug interaction of Glycopyrrolate/Glycopyrronium Bromide is with Parasympathomimetic, Monoamine Oxidase Inhibitor, Tricyclic antidepressant , Phenothiazine antipsychotics, antihistamines,  Amantadine , Metoclopramide , Domperidone , Cisapride ,
Ref :-   Book : Martindale    Page : 2520,1312   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  The antimuscarinics effects may be enhanced by use with other drugs having antimuscarinic properties, such as amantadine, some antihistamines, phenothiazine antipsychotics, and tricyclic antidepressants. Inhibition of drug-metabolising enzymes by MAOIs may possibly enhance the effects of antimuscarinics. The reduction in gastric motility caused by antimuscarinics may affect the absorption of other drugs. Antimuscarinics may also antagonise the gastrointestinal effects of cisapride, domperidone, and metoclopramide. Antimuscarinics and parasympathomimetics may counteract each others effects.,
Ref :-   Book : Martindale    Page : 2520,1312   Edition : 38,


►  Contraindication : Gastrointestinal obstruction, narrow-angle glaucoma,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 130   Edition : 3,
  ►  Mechanism of Action :   Selectively antagonize muscarinic receptors.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 130   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Gleditsia sinensis with Another pathway, Ephedra sinica with Another pathway, Rosmarinus officinalis with Another pathway, Vitex negundo with Another pathway, Tylophora indica with Another pathway, Adhatoda vasica Nees i. e. malabar nut with Another pathway, Albizzia lebbeck with Another pathway, Alstonia scholaris with Another pathway, Artemisia caerulescens with Another pathway, Belamcanda chinensis with Another pathway,

  ►  Pathway with its reference as follows :-
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Murray, A. (2013). Natural AChE Inhibitors from Plants and their Contribution to Alzheimer’s Disease Therapy. Curr Neuropharmacol, 11(4), 388–413. http://dx.doi.org/10.2174/1570159X11311040004 )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )
  • bronchodilator --- (Mali R. A review on herbal antiasthmatics. Oriental Pharmacy and Experimental Medicine. 2011;11(2):77–90. )

  •   ►  URL -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245822/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Renal,
    Ref :-   Book : Martindale    Page : 2520   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA