Goserelin is a Medicine belongs to sex hormone group whose information about Brand can be referenced from   Book : Martindale    Page : 2283   Edition : 38,

  ►   Brandname : Zoladex; Novgos

  ►  Strength : Injection with 3.6 ,10.8  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 677   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : SC,
Reference :-   Book : Martindale    Page : 2283   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Prostate cancer SC 3.6 mg Injection Once For 28 days.
2 Breast cancer SC 3.6 mg Injection Once For 28 days.
3 Endometriosis SC 3.6 mg Injection For up to 6 months.
4 Infertility SC 3.6 mg Injection 7 to 21 days.
5 Uterine fibroids SC 3.6 mg Injection Given with iron supplementation for up to 3 month before surgery.

Ref :-  Book : Martindale    Page : 2282   Edition : 38, Martindale    Page : 2283   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Precocious puberty SC 3.6 mg Injection o.d.

Ref :- Book : Martindale    Page : 2283   Edition : 38,
►  Side Effect : vaginal bleeding, nausea, abdominal pain, abdominal discomfort, hormonal milieu, mood changes, Nervousness, acne, palpitations, dry skin, changes in scalp and body hair, alterations in liver function tests , alterations in blood lipids, decrease in glucose tolerance, arthralgia, paraesthesia, thrombophlebitis, swelling, pruritus, hypersensitivity reactions, bronchospasm, anaphylaxis,
Ref :-   Book : Martindale    Page : 2283   Edition : 38, Martindale    Page : 2283,2282   Edition : 38,

►  Drug Interaction : Drug interaction of Goserelin is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : in patients with pituitary adenoma as haemorrhagic infarction (pituitary apoplexy), should be stopped if the patient becomes pregnant.,
Ref :-   Book : Martindale    Page : 2283,2282   Edition : 38,
  ►  Mechanism of Action :   Continuous Administration: inhibit LH and FSH release; pulsatile Administration: stimulate LH and FSH release.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 479   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 2283   Edition : 38,


►    Plasma Half-life :
  Min value :-   2 ,    Max value :-   4 hours,
Ref :-   Book : Martindale    Page : 2283   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA