Idoxuridine is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 985   Edition : 38,

  ►   Brandname : Idurin; Ridinox; Virunguent,Herpid

  ►  Strength : Eye Drop with   , Ophthalmic Ointment with 0.5  %, Ophthalmic Solution with 0.1  %,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 985   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical,
Reference :-   Book : Martindale    Page : 985   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Herpes simplex keratitis Topical 0.1 % Ophthalmic Solution
2 Herpes simplex keratitis Topical 0.5 % Eye ointment
3 Cutaneous herpes simplex and herpes zoster Topical 5 % q.i.d. In dimethyl sulfoxide may be painted onto the lesions for 4 days.

Ref :-  Book : Martindale    Page : 985   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : hypersensitivity reactions, Irritation, Pain, pruritus, stinging, conjunctivitis, oedema, photophobia, taste disturbances, inflammation of the eye or eyelids, skin maceration, ,
Ref :-   Book : Martindale    Page : 985   Edition : 38,

►  Drug Interaction : Drug interaction of Idoxuridine is with NA

  ►    Mechanism of Drug Drug Interaction :  Preparations containing boric acid should not be applied to the eye in patients also receiving ocular preparations of idoxuridine as irritation ensues. ,
Ref :-   Book : Martindale    Page : 985   Edition : 38,


►  Contraindication : deep ulceration involving the stromal layers of the cornea, as delayed healing has resulted in corneal perforation. Prolonged topical use should be avoided.,
Ref :-   Book : Martindale    Page : 985   Edition : 38,
  ►  Mechanism of Action :   After intracellular phosphorylation to the triphosphate, idoxuridine is incorporated into viral DNA instead of thymidine so inhibiting replication of sensitive viral strains. Idoxuridine is also incorporated into mammalian DNA. Idoxuridine is active against herpes simplex and varicella zoster viruses. It has also been shown to inhibit vaccinia virus, CMV, and adenovirus.,
Ref :-   Book : Martindale    Page : 985   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Turmeric with Another pathway,

  ►  Pathway with its reference as follows :-
  • Cucuritacins have Anti viral effect --- ( Prasad, S. (2016). Turmeric, the Golden Spice (2nd ed. )

  •   ►  URL -- https://books.google.co.in/books?id=7WDgesSflScC&printsec=frontcover&dq=Prasad, +S.+(2016).+Turmeric, +the+Golden+Spice+(2nd+ed.&hl=en&sa=X&redir_esc=y#v=onepage&q&f=false,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 985   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA