Isoflurane is a Medicine belongs to General anaesthetics group whose information about Brand can be referenced from   Book : Martindale    Page : 1905   Edition : 38,

  ►   Brandname : Forane,AErrane

  ►  Strength : Liquid with 100  mL,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 446   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : inhalation,
Reference :-   Book : Martindale    Page : 1903   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 For induction inhalation Liquid It is given with oxygen or oxygen and nitrous oxide mixtures and induction should start with an isoflurane concentration of 0.5% v/v increased to 1.5 to 3% v/v which generally produces surgical anaesthesia within 10 minutes.
2 To maintain anaesthesia for caesarean section inhalation 0.5 0.75 % v/v Liquid With oxygen and nitrous oxide mixtures.

Ref :-  Book : Martindale    Page : 1903   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : respiratory depression, hypotension, arrhythmia, Malignant hyperthermia, increased cerebral blood flow, Breath holding, coughing, laryngospasm,
Ref :-   Book : Martindale    Page : 1904   Edition : 38,

►  Drug Interaction : Drug interaction of Isoflurane is with Atracurium ,
Ref :-   Book : Martindale    Page : 1904   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  competitive neuromuscular blockers such as atracurium are enhanced by isoflurane,
Ref :-   Book : Martindale    Page : 1904   Edition : 38,


►  Contraindication : should be used with caution in patients with raised intracranial pressure.,
Ref :-   Book : Martindale    Page : 1904   Edition : 38,
  ►  Mechanism of Action :   Modulation of ligand-gated ion channels.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 260   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   lungs,
Ref :-   Book : Martindale    Page : 1904   Edition : 38,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA