Ivermectin is a Medicine belongs to Antihelminthic Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 157   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Mectizan,Stromectol; Ectin; Ectover; Elect; Ivor,Bandy Plus

  ►  Strength : Tablet with 3  mg, Tablet with 6  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 946   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 155   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Onchocerciasis Oral 150 micrograms/kg Tablet Single dose.
2 Strongyloidiasis Oral 200 micrograms/kg Tablet As a single dose, or daily on two consecutive days.
3 Head pediculosis Topical 0.5 % Lotion

Ref :-  Book : Martindale    Page : 155   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Onchocerciasis more than 5 Year over 15 kg Oral 150 micrograms/kg Tablet
2 Spondylitis more than 5 Year over 15 kg Oral 200 micrograms/kg Tablet
3 Head pediculosis 6 Month Topical 0.5 % Lotion

Ref :- Book : Martindale    Page : 155   Edition : 38,
►  Side Effect : fever, pruritus, Rashes, arthralgia, myalgia, asthenia, Orthostatic hypotension, tachycardia, oedema, lymphadenopathy, gastrointestinal symptoms, sore throat, cough, and headache, mild ocular irritation, Somnolence, transient eosinophilia, raised liver enzyme values,
Ref :-   Book : Martindale    Page : 156   Edition : 38,

►  Drug Interaction : Drug interaction of Ivermectin is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : pregnancy,
Ref :-   Book : Martindale    Page : 156   Edition : 38,
  ►  Mechanism of Action :   Ivermectin probably binds to glutamate-activated Cl– channels found in nematode nerve or muscle cells, and causes hyperpolarization by increasing intracellular chloride concentration. This results in paralysis of the parasite.,
Ref :-   Book : Goodman    Page : 1455   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Bhringraj with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anthelmintic effect --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Hepatic (Metabolism), Renal, breast milk,
    Ref :-   Book : Martindale    Page : 157   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   12 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 157   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   4 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 157   Edition : 38,