Latanoprost is a Medicine belongs to antiglaucoma drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2044   Edition : 37,

  ►   Brandname : Xalatan,9PM

  ►  Strength : Ophthalmic Solution with 0.005  %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 328   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : ophthalmic,
Reference :-   Book : Martindale    Page : 2044   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Open-angle glaucoma ophthalmic 0.005 % Ophthalmic Solution o.d. Dose: instilled preferably in the evening
2 Ocular hypertension ophthalmic 0.005 % Ophthalmic Solution o.d. Dose: instilled preferably in the evening

Ref :-  Book : Martindale    Page : 2044   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Increase in the amount of brown pigment in the iris, Change in eye colour, Darkening, thickening, and lengthening of eye lashes, Ocular irritation, conjunctival hyperaemia, transient punctate epithelial erosions , eyelid oedema, Dizziness, headache, arthralgia, myalgia, ,
Ref :-   Book : Martindale    Page : 2044   Edition : 37,

►  Drug Interaction : Drug interaction of Latanoprost is with NA

  ►    Mechanism of Drug Drug Interaction :  Paradoxical increases in intra-ocular pressure. ,
Ref :-   Book : Martindale    Page : 2044   Edition : 37,


►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►  Mechanism of Action :   Latanoprost, bind to FP receptors that link to Gq11 and then to the PLC–IP3–Ca2+ pathway. This pathway is active in isolated human ciliary muscle cells. Other cells in the eye also may express FP receptors. Theories of IOP lowering by PGF2 range from altered ciliary muscle tension to effects on trabecular meshwork cells to release of matrix metalloproteinases and digestion of extracellular matrix materials that may impede outflow tracts.,
Ref :-   Book : Goodman    Page : 1787   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti-Glaucoma property --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- IRON with Dietary Substance is Drug Inhibitor,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA