Leucovorin (calcium) is a Medicine belongs to group whose information about Brand can be referenced from   Book : Martindale    Page : 2103   Edition : 37,

  ►   Brandname : Biovorin

  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV, IM,
Reference :-   Book : Martindale    Page : 2102   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : oedema, hypertension, hypokalaemic alkalosis, delayed wound healing, increased susceptibility to infection, perforation of the nasal septum,
Ref :-   Book : Martindale    Page : 1681   Edition : 37,

►  Drug Interaction : Drug interaction of Leucovorin (calcium) is with Mycophenolate mofetil , liraglutide , Diazoxide , Zonisamide , Methotrexate, Pyrimethamine , Triamterene , Trimethoprim , Salbutamol , Phenytoin ,
Ref :-   Book : Martindale    Page : 2098.1   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  NA


►  Contraindication : vitamin B12 deficiency,
Ref :-   Book : Martindale    Page : 2098   Edition : 37,
  ►  Mechanism of Action :   NA

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Milk & milk products with same compound, Castor with Another pathway,

  ►  Pathway with its reference as follows :-
  • Nutritional Supplement --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )
  • immunostimulant effect --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- https://books.google.co.in/books?id=biFBAAAAYAAJ&q=Gopalan, +C., +Rama+Sastri, +B., +%26+Balasubramanian, +S.+(1971).+Nutritive+value+of+Indian+foods.+Hyderabad, +India:+National+Institute+of+Nutrition, +Indian+Counc, http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA