Levamisole is a Medicine belongs to Antihelminthic Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 156   Edition : 37  

  ►   Brandname : Ergamisol, Levomol, Vermisol, Vizole
  ►  Strength : Tablet with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 156   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 155   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Hookworm infection or for mixed ascariasis- hookworm infections Oral 2.5 mg/kg Tablet Dose: Given as single dose.
2 Ascariasis Oral 2.5 mg/kg Tablet Dose: Given as single dose.

Ref :-  Book : Martindale    Page : 155   Edition : 37  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Ascariasis Oral 2.5 mg/kg Tablet
2 Hookworm infections Oral 2.5 mg/kg Tablet
3 Mixed ascariasis-hookworm infections Oral 2.5 mg/kg Tablet

Ref :- Book : Martindale    Page : 155   Edition : 37  
►  Side Effect : Nausea, Vomiting, Diarrhoea, Abdominal pain, Dizziness, Headache, Hypersensitivity reactions, Fever, Flu-like syndrome, Arthralgia, Muscle pain, Skin rashes, Cutaneous vasculitis, Insomnia, Convulsion, Agranulocytosis, leucopenia, Thrombocytopenia, Gastrointestinal disturbance, Abnormal taste in the mouth
Ref :-   Book : Martindale    Page : 155   Edition : 37.  

►  Drug Interaction : Drug interaction of Levamisole is with Alcohol,  Warfarin , Phenytoin
Ref :-   Book : Martindale    Page : 155   Edition : 37.  


  ►    Mechanism of Drug Drug Interaction :  Levamisole can produce a disulfiram-like reaction with alcohol. For an increase in the activity of warfarin when given with levamisole and fluorouracil. For increased phenytoin concentrations when given with levamisole and fluorouracil.
Ref :-   Book : Martindale    Page : 155   Edition : 37.  


►  Contraindication : Blood disorders, Patients given levamisole with fluorouracil should undergo appropriate monitoring of haematological and hepatic function
Ref :-   Book : Martindale    Page : 155   Edition : 37.  
  ►  Mechanism of Action :   Levamisole hydrochloride is the active laevo-isomer of tetramisole hydrochloride. Levamisole is active against intestinal nematode worms and appears to act by paralysing susceptible worms which are subsequently eliminated from the intestines.
Ref :-   Book : Martindale    Page : 155   Edition : 37.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal, Faecal
Ref :-   Book : Martindale    Page : 155   Edition : 37.  

►    Plasma Half-life :   Min value :-   3 hours,    Max value :-   4 hours.  
Ref :-   Book : Martindale    Page : 155   Edition : 37.  

►    Peak Plasma Concentration :   Min value :-   1.5 hours,    Max value :-   2 hours.  
Ref :-   Book : Martindale    Page : 155   Edition : 37.