Levocetirizine is a Medicine belongs to Antihistamine (H1 blocker) group whose information about Brand can be referenced from   Book : Martindale    Page : 634   Edition : 37      Page :   Edition :   

  ►   Brandname : Xyzall, Xusal, L-Cetridoc , Leset, Levorid, Teczine, Montair LC
  ►  Strength : Tablet with 5 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 292   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page :    Edition : 634  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Symptomatic relief of allergic conditions including rhinitis and chronic urticaria Oral 5 mg Tablet o.d.

Ref :-  Book : Martindale    Page : 634   Edition : 37  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Symptomatic relief of allergic rhinitis and chronic idiopathic urticaria 2 Year 6 Year Oral 2.5 mg

Ref :- Book : Martindale    Page : 634   Edition : 37  
►  Side Effect : Non-sedating antihistamines is that most have little or no antimuscarinic effect, Nausea, Vomiting, Diarrhoea, Epigastric pain, palpitations, Arrhythmias, Rashes, Hypersensitivity reactions, Bronchospasm, Angioedema, Anaphylaxis, Convulsion, Sweating, Myalgia, Paraesthesia, Extrapyramidal effects, Tremor, Sleep disturbances, Depression, Confusion, Tinnitus, Hypotension, Hair loss
Ref :-   Book : Martindale    Page : 611,621,634   Edition : 37.  

►  Drug Interaction : Drug interaction of Levocetirizine is with NA

  ►    Mechanism of Drug Drug Interaction :  Potentially hazardous ventricular arrhythmias have occurred when the non-sedating antihistamines have been given with drugs liable to interfere with their hepatic metabolism, with other potentially arrhythmogenic drugs including those that prolong the QT interval, or with those likely to cause electrolyte imbalance. However, some interactions are less likely with levocetirizine than with non-sedating antihistamines such as astemizole and terfenadine, since levocetirizine appears to have low hepatic metabolism and little arrhythmogenic potential
Ref :-   Book : Martindale    Page : 613,621,634   Edition : 37.  

►  Contraindication : In the case of non-sedating antihistamines, although drowsiness is rare, it can occur and may affect the performance of skilled tasks, Convulsions, Caution in patients with epilepsy, Renal impairment, Hepatic impairment, Increase the risk of arrhythmias, Known or suspected prolongation of the QT interval, Hypokalaemia, Electrolyte imbalance, It should be avoided in neonates, young children, elderly patients
Ref :-   Book : Martindale    Page : 612,621,634   Edition : 37.  
  ►  Mechanism of Action :   Inverse agonists that bind preferentially to the inactive conformation of the H1 receptor and shift the equilibrium toward the inactive receptor state.
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 775   Edition : 3.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA

DIETARY Substance Interactions

​   ► This Medicine interact with :- NA

ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   8 hours,    Max value :-   9 hours.  
Ref :-   Book : Goodman    Page : 1816   Edition : 12.  

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA