Mebeverine is a Medicine belongs to Gastrointestinal drug group whose information about Brand can be referenced from   Book : Martindale    Page : 1859   Edition : 38  

  ►   Brandname : Colospa, Libure, Mebrin, Colofac, IBS Relief
  ►  Strength : Tablet with .  Oral liquid with N.F.R.B

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1858   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 1858   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Irritable bowel syndrome Oral 135 mg Tablet t.i.d. Before meals; 100 mg three times daily has also been used. A modified-release preparation is also available, taken as 200 mg twice daily.
2 Irritable bowel syndrome Oral 150 mg Oral liquid t.i.d.

Ref :-  Book : Martindale    Page : 1858   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Symptomatic relief of gastrointestinal smooth muscle spasm 3 Year 4 Year Oral 25 mg t.i.d.
2 Symptomatic relief of gastrointestinal smooth muscle spasm 4 Year 8 Year Oral 50 mg t.i.d.
3 Symptomatic relief of gastrointestinal smooth muscle spasm 8 Year 10 Year Oral 100 mg t.i.d.
4 Symptomatic relief of gastrointestinal smooth muscle spasm 10 Year 18 Year Oral 135 mg Tablet t.i.d.

Ref :- Book : Martindale    Page : 1858   Edition : 38  
►  Side Effect : , Hypersensitivity reactions, Erythematous rash, Urticaria, Angioedema
Ref :-   Book : Martindale    Page : 1858   Edition : 38.  

►  Drug Interaction : Drug interaction of Mebeverine is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Paralytic ileus
Ref :-   Book : Martindale    Page : 1858   Edition : 38.  
  ►  Mechanism of Action :   Mebeverine hydrochloride is an antispasmodic with a direct action on the smooth muscle of the gastrointestinal tract.
Ref :-   Book : Martindale    Page : 1858   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal
Ref :-   Book : Martindale    Page : 1159   Edition : 38.  

►    Plasma Half-life :   Min value :-   N.F.R.B,    Max value :-   NA
Ref :-   Book :    Page :    Edition : .  

►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   3 hours.  
Ref :-   Book : Martindale    Page : 1859   Edition : 38.