Melitracen is a Medicine belongs to Antidepressant group whose information about Brand can be referenced from   Book : Martindale    Page : 434   Edition : 38  

  ►   Brandname : Ambulax- FM
  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 434   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Depression Oral 25 mg b.d/t.i.d Increased as necessary to a maximum of 225 mg daily.
2 Depression with anxiety Oral A combination of melitracen 10 mg and flupentixol 500 micrograms is given orally in the morning and at midday. In severe cases the morning dose may be doubled. The total daily dose should not exceed melitracen 40 mg and flupentixol 2 mg. Elderly patients may be given melitracen 10 mg with flupentixol 500 micrograms in the morning; in severe cases this dose may be given in the morning and at midday.

Ref :-  Book : Martindale    Page : 434   Edition : 38  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :    Page :    Edition :   
►  Side Effect : Dry mouth, Constipation, Urinary retention, Blurred Vision, Disturbances in accommodation, Increased intraocular pressure, Hyperthermia, Nervousness, Insomnia, Headache, Peripheral neuropathy, Tremor, Ataxia, Epileptiform seizures, Tinnitus, Extrapyramidal symptoms, Speech Difficulties, Confusion, Hallucinations, Delirium, Mania, Hypomania, Behavioural disturbances, Orthostatic hypotension, Tachycardia, Gastrointestinal complaints include sour or metallic taste, stomatitis, and gastric irritation with nausea and vomiting., Hypersensitivity reactions, Urticaria, Angioedema, Photosensitisation, , Testicular enlargement, Gynaecomastia, breast enlargement, Galactorrhoea, Sexual dysfunction, Increased appetite, Weight gain
Ref :-   Book : Martindale    Page : 434,402   Edition : 38.  

►  Drug Interaction : Drug interaction of Melitracen is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R, B
Ref :-   Book :    Page :    Edition : .  

►  Contraindication :
Ref :-   Book :    Page :    Edition : .  
  ►  Mechanism of Action :   They inhibit the neuronal reuptake of noradrenaline in the CNS; some, in addition, inhibit the reuptake of serotonin (5-HT). Prevention of the reuptake of these monoamine neurotransmitters, which potentiates their action in the brain, appears to be associated with antidepressant activity.
Ref :-   Book : Martindale    Page : 434,401   Edition : 38.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA

DIETARY Substance Interactions

​   ► This Medicine interact with :- NA

ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA