Meloxicam is a Medicine belongs to Non Sterodial Anti- Inflammatory Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 87   Edition : 38,

  ►   Brandname : Mobic; Ecwin; M-Cam

  ►  Strength : Tablet with 7.5  mg, Tablet with 15  mg, Suspension with 7.5/5  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 656   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 87   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Osteoarthritis Oral 7.5 mg Tablet Daily, increased if necessary to a maximum of 15 mg daily given as a single dose.
2 Rheumatoid arthiritis Oral 15 mg Tablet Given as a single dose.
3 Ankylosing spondylitis Oral 15 mg Tablet Given as a single dose.

Ref :-  Book : Martindale    Page : 86   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Juvenile idiopathic arthritis 2 Year over 2 Year Oral 125 micrograms/kg Tablet o.d.

Ref :- Book : Martindale    Page : 86   Edition : 38,
►  Side Effect : gastrointestinal perforation, ulceration, gastrointestinal bleeding, pruritus, Rashes, Urticaria, angioedema, photosensitivity, Bullous dermatoses, including erythema multiforme and Stevens-Johnson syndrome., Dizziness, flushing, fatigue, , dyspepsia, gastrointestinal disturbance,
Ref :-   Book : Martindale    Page : 87   Edition : 38,

►  Drug Interaction : Drug interaction of Meloxicam is with NA

  ►    Mechanism of Drug Drug Interaction :  Colestyramine increases the clearance and decreases the half-life of meloxicam., ,
Ref :-   Book : Martindale    Page : 87   Edition : 38,    Page :    Edition : ,


►  Contraindication : Severe hepatic impairment, bleeding disorders, proctitis, haemorrhoids, or rectal bleeding., Highest risk of ulcer, perforation, ulcerative colitis , crohn disease, severe heart failure, Moderate to severe heart failure, ischaemic heart disease, peripheral arterial disease, Cerebrovascular disease, hypertension, ventricular dysfunction , Oedema, asthma, allergic disorder, Peptic ulceration,
Ref :-   Book : Martindale    Page : 87   Edition : 38, Martindale    Page : 87,107   Edition : 38,
  ►  Mechanism of Action :   It is oxicam derivative, It is a selective inhibitor of cyclo-oxygenase-2 (COX-2), The principal therapeutic effects of NSAIDs derive from their ability to inhibit PG production. The first enzyme in the PG synthetic pathway is COX, also known as PG G/H synthase. This enzyme converts AA to the unstable intermediates PGG2 and PGH2 and leads to the production of the prostanoids, TxA2, and a variety of PGs. Meloxicam exhibit selectivity for COX-2 that is close to that of celecoxib in vitro. All NSAIDs, including selective COX-2 inhibitors, are antipyretic, analgesic, and anti-inflammatory.,
Ref :-   Book : Martindale    Page : 85   Edition : 37, Goodman    Page : 963,965   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- LITHIUM with Most NASDs inhibit the exretion of lithium from the body , resulting in higher blood levels of the mineral , though sulindac .,

  ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,

    ►   Route of Elimination :   Fecal, Renal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 87   Edition : 38,


    ►    Plasma Half-life :   Min value :-   20 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 87   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   6 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 87   Edition : 38,