Mepacrine is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 936   Edition : 38,

  ►   Brandname : Maladin

  ►  Strength : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 935   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, Local,
Reference :-   Book : Martindale    Page : 935   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Giardiasis Oral 100 mg t.i.d. After food for 5 to 7 days.

Ref :-  Book : Martindale    Page : 935   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Giardiasis Oral 2 mg/kg t.i.d.

Ref :- Book : Martindale    Page : 935   Edition : 38,
►  Side Effect : Dizziness, headache, gastrointestinal disturbance, nausea, vomiting, Reversible yellow discoloration of the skin, conjunctiva, and urine, transient acute toxic psychosis, blue/black discoloration of the palate and discoloration of the nails, convulsion, CNS stimulation, aplastic anaemia, chronic dermatoses, including severe exfoliative dermatitis and lichenoid eruptions,, ,
Ref :-   Book : Martindale    Page : 935   Edition : 38,

►  Drug Interaction : Drug interaction of Mepacrine is with Alcohol,  Primaquine ,
Ref :-   Book : Martindale    Page : 936   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Mepacrine has been reported to produce a mild disulfiram-like reaction when taken with alcohol. Theoretically, mepacrine may increase the plasma concentrations of primaquine resulting in a higher risk of toxicity, and it has been recommended that these drugs should not be used together.,
Ref :-   Book : Martindale    Page : 936   Edition : 38,


►  Contraindication : in elderly patients or patients with a history of psychosis, or in the presence of hepatic disease. Mepacrine can cause exacerbation of psoriasis and should be avoided in psoriatic patients.,
Ref :-   Book : Martindale    Page : 936   Edition : 38,
  ►  Mechanism of Action :   ,
Ref :-   Book :    Page :    Edition : ,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal,
Ref :-   Book : Martindale    Page : 936   Edition : 38,


►    Plasma Half-life :
  Min value :-   5 days,    Max value :-   NA
Ref :-   Book : Martindale    Page : 936   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   1,    Max value :-   3 hours,
Ref :-   Book : Martindale    Page : 936   Edition : 38,