Methandrostenolone is a Medicine belongs to sex hormone group whose information about Brand can be referenced from   Book :

  ►   Brandname : NA
  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 2291   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Increased retention of sodium and water, oedema, hypercalcaemia, and impaired glucose tolerance. Other effects include increased lowdensity- lipoprotein cholesterol, decreased high-density- lipoprotein cholesterol, increased haematocrit, Suppression of clotting factors, Headache, Depression, irritability, Aggression, Gastrointestinal disturbance, Gastrointestinal bleeding, Sleep apnoea, Cholestatic hepatitis, Jaundice, Hepatic tumours in patients who have received high doses over prolonged periods., Epididymitis, Bladder irritability, Gynaecomastia, Prostatic hyperplasia, Suppression of ovarian activity and menstruation., Symptoms of virilism, such as hirsutism or male-pattern baldness, deepening of the voice, atrophy of the breasts and endometrial tissue, oily skin, acne, and hypertrophy of the clitoris.
Ref :-   Book : Martindale    Page : 2291,2307   Edition : 38.  

►  Drug Interaction : Drug interaction of Methandrostenolone is with Neuromuscular blocker , Oral Antidiabetic Drugs,  Cyclosporine , Levothyroxine, Warfarin , Insulin
Ref :-   Book : Martindale    Page : 2291,2308   Edition : 38.  

  ►    Mechanism of Drug Drug Interaction :  Methandrostenolone enhance the activity of a number of drugs, with resulting increases in toxicity. Drugs affected include ciclosporin, levothyroxine and anticoagulants such as warfarin. Resistance to the effects of neuromuscular blockers has also been reported. As androgens and anabolic steroids can alter glucose metabolism, doses of insulin or oral antidiabetics may need adjustment.
Ref :-   Book : Martindale    Page : 2291,2308   Edition : 38.  

►  Contraindication : Avoided in patients with hepatic impairment and certainly if this is severe.
Ref :-   Book : Martindale    Page : 2291   Edition : 38.  
  ►  Mechanism of Action :   Methandrostenolone has anabolic and some androgenic properties, controls the development and maintenance of the male sex organs and the male secondary sex characteristics. It also produces systemic anabolic effects, such as increased retention of nitrogen, calcium, sodium, potassium, chloride, and phosphate. This leads to an increase in water retention and bone growth. The skin becomes more vascular and less fatty and erythropoiesis is increased.
Ref :-   Book : Martindale    Page : 2291,2305,2231   Edition : 38.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA

DIETARY Substance Interactions

​   ► This Medicine interact with :- NA

ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA