Methionine or L-methionine is a Medicine belongs to Antidote group whose information about Brand can be referenced from   Book :    Page :   Edition : , Martindale    Page : 1591   Edition : 37,

  ►   Brandname : health ok,Acimethin, M-Caps, Pedameth, Uracid

  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1591   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Paracetamol poisoning Oral 2.5 gm Given every 4 hours for 4 doses starting less than 10 to 12 hours after ingestion of the paracetamol.

Ref :-  Book : Martindale    Page : 1591   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, drowsiness, irritability,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,

►  Drug Interaction : Drug interaction of Methionine or L-methionine is with Activated charcoal ,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Methionine may be adsorbed by activated charcoal and the effect of oral methionine may be reduced if they are given together.,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,


►  Contraindication : Methionine may aggravate hepatic encephalopathy in patients with established liver damage; it should be used with caution in patients with severe liver disease.,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,
  ►  Mechanism of Action :   L-Methionine is an essential amino acid. Methionine also enhances the synthesis of glutathione and is used as an alternative to acetylcysteine in the treatment of paracetamol poisoning to prevent hepatotoxicity,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1591   Edition : 37,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA