Methocarbamol is a Medicine belongs to muscle relaxant (Spasmolytic) group whose information about Brand can be referenced from   Book : Martindale    Page : 2026   Edition : 38,

  ►   Brandname : Robinax; Robaxin

  ►  Strength : Tablet with 500  mg, Tablet with 750  mg, Injection with 100  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV infusion, IM,
Reference :-   Book : Martindale    Page : 2025   Edition : 38, Martindale    Page : 2026   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Muscle spasm Oral 1.5 gm Tablet q.i.d.
2 Muscle spasm IM 500 mg Injection t.i.d.
3 Muscle spasm slow IV injection/infusion Injection At a rate of not more than 300 mg/minute, by slow injection or by infusion in sodium chloride 0.9% or glucose 5% injection.

Ref :-  Book : Martindale    Page : 2026   Edition : 38, Martindale    Page : 2025   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, anorexia, lightheadedness, Dizziness, lassitude, drowsiness, Restlessness, anxiety, Confusion, tremor, vertigo, Blurred Vision, fever, headache, convulsion, hypersensitivity reactions, Rashes, pruritus, Urticaria, angioedema, conjunctivitis, nasal congestion, flushing, metallic taste, incoordination, diplopia, nystagmus, syncope, hypotension, bradycardia, anaphylaxis, sloughing, thrombophlebitis,
Ref :-   Book : Martindale    Page : 2026   Edition : 38,

►  Drug Interaction : Drug interaction of Methocarbamol is with Alcohol, CNS depressant, Anorectics, Antimuscarinic,  Pyridostigmine ,
Ref :-   Book : Martindale    Page : 2026   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  The CNS effects of methocarbamol may be potentiated by alcohol or other CNS depressants. Methocarbamol has also been reported to potentiate the effects of anorectics and antimuscarinics, and to inhibit the effect of pyridostigmine,
Ref :-   Book : Martindale    Page : 2026   Edition : 38,


►  Contraindication : coma, Pre-coma states, Brain damage, Myasthenia gravis, history of epilepsy, renal impairment, hepatic impairment,
Ref :-   Book : Martindale    Page : 2026   Edition : 38,
  ►  Mechanism of Action :   Methocarbamol is a centrally acting skeletal muscle relaxant whose action may be due to general depressant effects on the CNS. ,
Ref :-   Book : Martindale    Page : 2025   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Poppy seed with Another pathway,

  ►  Pathway with its reference as follows :-
  • muscle relaxant . --- ( Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- with Cause excessive drawsinesss when taken with muscle relaxcent .,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand.

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 2026   Edition : 38,


    ►    Plasma Half-life :   Min value :-   1 hours,    Max value :-   2 hours,
    Ref :-   Book : Martindale    Page : 2026   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA