Mianserin is a Medicine belongs to Antidepressant group whose information about Brand can be referenced from   Book : Martindale    Page : 439   Edition : 37,

  ►   Brandname : Lumin,Tolvon

  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 429   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Depression Oral 30 40 mg Tablet Daily.

Ref :-  Book : Martindale    Page : 439   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : drowsiness, bone marrow depression, leucopenia, granulocytopenia, agranulocytosis, aplastic anaemia, Liver dysfunction, jaundice, breast disorders, Gynaecomastia, nipple tenderness, non-puerperal lactation, polyarthropathy, cardiac failure, ventricular fibrillation, bradycardia, frequent ventricular ectopic beats, toxic epidermal necrolysis, glossitis,
Ref :-   Book : Martindale    Page : 439   Edition : 37,

►  Drug Interaction : Drug interaction of Mianserin is with Phenelzine, Phenytoin , Zonisamide , Bezafibrate , ,
Ref :-   Book : Martindale    Page : 439.2   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Mianserin may antagonise the action of antiepileptics by lowering the convulsive threshold.,
Ref :-   Book : Martindale    Page : 439   Edition : 37,


►  Contraindication : hepatic impairment, Porphyria,
Ref :-   Book : Martindale    Page : 439   Edition : 37,
  ►  Mechanism of Action :   Mianserin is a tetracyclic antidepressant. It does not appear to have significant antimuscarinic properties, but has a marked sedative action. Unlike the tricyclic antidepressants, mianserin does not prevent the peripheral reuptake of noradrenaline; it blocks presynaptic adrenergic (α2) receptors and increases the turnover of brain noradrenaline. Mianserin is also an antagonist of postsynaptic serotonin receptors in some parts of the brain,
Ref :-   Book : Martindale    Page : 439   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 439   Edition : 37,


►    Plasma Half-life :
  Min value :-   6 hours,    Max value :-   40 hours,
Ref :-   Book : Martindale    Page : 439   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,