Miconazole nitrate is a Medicine belongs to Antifungal group whose information about Brand can be referenced from   Book : Martindale    Page : 590   Edition : 37,

  ►   Brandname : Daktarin,Gyno-Daktarin,Micogel,Zole,Loramyc,Absorbine Antifungal Foot Powder,Breezee Mist Antifungal,Femizol-M

  ►  Strength : Cream with 2  %, Powder with 2  %, Spray with 2  %, Suppository with 100  mg, Suppository with 200  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 858   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical, IV, Oral, rectal,
Reference :-   Book : Martindale    Page : 589   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, diarrhoea, allergic reactions, hepatitis, local irritation, sensitivity reactions, phlebitis, anorexia, pruritus, Rashes, febrile reactions, flushing, drowsiness, hyponatraemia, hyperlipidaemia, aggregation of erythrocytes, anaemia, transient tachycardia, cardiac arrhythmia, thrombocytosis,
Ref :-   Book : Martindale    Page : 589   Edition : 37,

►  Drug Interaction : Drug interaction of Miconazole nitrate is with Ropinirole , , Phenytoin , Astemizole, Cisapride , Dofetilide , Halofantrine, Mizolastine, Pimozide , Quinidine , Sertindole, Terfenadine,
Ref :-   Book : Martindale    Page : 589   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Miconazole can inhibit the metabolism of drugs metabolised by the cytochrome P450 isoenzymes CYP3A4 and CYP2C9, and may thus have effects similar to those of fluconazole. Miconazole may enhance the activity of oral anticoagulants, sulfonylurea hypoglycaemics, or phenytoin. There is a risk of cardiac arrhythmias if miconazole is used with substrates of CYP3A4 that may prolong the QT interval, such as astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, or terfenadine and such combinations should be avoided.,
Ref :-   Book : Martindale    Page : 589   Edition : 37,


►  Contraindication : hepatic impairment,
Ref :-   Book : Martindale    Page : 589   Edition : 37,
  ►  Mechanism of Action :   Reduces ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes. ,
Ref :-   Book : Basic & Clinical pharmacology    Page : 853   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 589   Edition : 38,


►    Plasma Half-life :
  Min value :-   24 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 589   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   4 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 589   Edition : 37,