Mifepristone is a Medicine belongs to Antiprogestins/obsteric drug group whose information about Brand can be referenced from   Book : Martindale    Page : 2174   Edition : 37,

  ►   Brandname : Mifegest,MT Pill,Mifegyne,Mifeprex

  ►  Strength : Tablet with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, ,
Reference :-   Book : Martindale    Page : 2174   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Fetal death Oral 600 mg Tablet Given daily for 2 consecutive day.
2 Termination of pregnancy Oral 600 mg Tablet Termination of pregnancies of up to 49 days.
3 Softening and dilatation of the cervix Oral 200 mg Tablet Given 36 to 48 hours before the procedure labour induction.

Ref :-  Book : Martindale    Page : 2138   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
Precaution :- If a Patient is using 'Mifepristone' drug in  Medical Termination of Pregnancy  disease, then Please Contraindication: Haemorrhagic disorder .

►  Side Effect : malaise, Dizziness, chills, fever, headache, diarrhea, nausea, vomiting, Skin rashes,
Ref :-   Book : Martindale    Page : 2173   Edition : 37,

►  Drug Interaction : Drug interaction of Mifepristone is with Aspirin,
Ref :-   Book : Martindale    Page : 2174   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  The metabolism of mifepristone is mediated by the cytochrome P450 isoenzyme CYP3A4. Theoretically, use with other drugs that inhibit or induce this isoenzyme may result in changes in plasma concentration of mifepristone. In-vitro studies indicate that mifepristone itself inhibits CYP3A4; it should be used cautiously with CYP3A4 substrates that have a narrow therapeutic index,
Ref :-   Book : Martindale    Page : 2174   Edition : 37,


►  Contraindication : ectopic pregnancy, asthma, renal impairment, hepatic impairment, Haemorrhage, cardiovascular disease, anemia, Porphyria, ,
Ref :-   Book : Martindale    Page : 2173   Edition : 37,
  ►  Mechanism of Action :   Mifepristone is a steroid derived from norethisterone that has potent antiprogestogenic activity,
Ref :-   Book : Martindale    Page : 2174   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal,
Ref :-   Book : Martindale    Page : 2174   Edition : 37,


►    Plasma Half-life :
  Min value :-   18 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 2174   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   2 hours,
Ref :-   Book : Martindale    Page : 2174   Edition : 37,