Minocycline is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 326   Edition : 38,

  ►   Brandname : CNN,Cynomycin,Aknemin,Dentomycin,Minocin,Sebomin,Sebren,Arestin,Cleeravue-M,Dynacin,Minocin,Myrac,Solodyn

  ►  Strength : Tablet with 20  mg, Tablet with 50  mg, Tablet with 75  mg, Tablet with 100  mg, Capsule with 20  mg, Capsule with 50  mg, Capsule with 75  mg, Capsule with 100  mg, Suspension with 50/5  mg/ml, Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 819   Edition : 12, Martindale    Page : 326   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV infusion, Topical, IM,
Reference :-   Book : Martindale    Page : 325   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Leprosy Oral 200 mg Tablet/Capsule Daily in divided doses.
2 Acne Oral 50 mg Tablet/Capsule b.d. or 100 mg once daily.
3 Multibacillary leprosy Oral 100 mg Tablet/Capsule Daily with clofazimine and ofloxacin or 100 mg monthly with rifampicin and ofloxacin have been recommended by WHO as alternative multidrug therapy regimens.
4 Asymptomatic meningococcal carriers Oral 100 mg Tablet/Capsule b.d. For 5 days.
5 Periodontal infections Topical 2 % Gel

Ref :-  Book : Martindale    Page : 325   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 over 8 Year Oral 4 mg/kg Tablet/Capsule

Ref :- Book : Martindale    Page : 325   Edition : 38,
►  Side Effect : gastrointestinal disturbance, oesophageal ulceration, Dizziness, vertigo, , lupus-like syndrome, serum-sickness-like syndrome, Hypersensitivity syndrome, arthralgia, fever, joint stiffness or swelling, hyperpigmentation of the skin,
Ref :-   Book : Martindale    Page : 325   Edition : 38,

►  Drug Interaction : Drug interaction of Minocycline is with , ,  NA

  ►    Mechanism of Drug Drug Interaction :  Minocycline has a lower affinity for binding with calcium than tetracycline. Consequently its absorption is less likely to be affected by milk or food, although it is still affected by calcium-containing antacids and other divalent and trivalent cations such as aluminium, bismuth, iron, magnesium, and zinc.,
Ref :-   Book : Martindale    Page : 326   Edition : 38,


►  Contraindication : Last half of pregnancy, Infancy, childhood up to 8 years of age,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 597   Edition : 3,
  ►  Mechanism of Action :   Bind to 16S rRNA of the 30S ribosomal subunit and inhibit protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the mRNA-ribosome complex. ,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 591   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- CALCIUM with Dietary Substance is Drug Inhibitor, MAGNESIUM with Dietary Substance is Drug Inhibitor, ZINC with Dietary Substance is Drug Inhibitor, IRON with Dietary Substance is Drug Inhibitor, CALCIUM with Decrease in Nutrient Level, VITAMIN K with Decrease in Nutrient Level,

  ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20, http://www.wjgnet.com/1948-9358/,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- PROBIOTICS with It reduice the side effect such as diarrhea .,

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.wjgnet.com/1948-9358/,

    ►   Route of Elimination :   Fecal, Renal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 326   Edition : `38, Martindale    Page : 326   Edition : 38,


    ►    Plasma Half-life :   Min value :-   16 hours after the first dose and 21 hours after repeated doses.,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 326   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   4 hours,
    Ref :-   Book : Martindale    Page : 326   Edition : 38,