Mivacurium Chloride is a Medicine belongs to Neuromuscular blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 2035   Edition : 38,

  ►   Brandname : Mivacron

  ►  Strength : Injection with 0.5  mg/ml, Injection with 2  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV infusion,
Reference :-   Book : Martindale    Page : 2034   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Endotracheal intubation and to provide muscle relaxation in general anaesthesia for surgical procedures IV 70 250 micrograms/kg Injection Doses up to 150 micrograms/kg may be given over 5 to 15 seconds but higher doses should be given over 30 seconds.

Ref :-  Book : Martindale    Page : 2034   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Endotracheal intubation and to provide muscle relaxation in general anaesthesia for surgical procedures over 12 Year IV 70 250 microgram/kg Injection
2 Endotracheal intubation and to provide muscle relaxation in general anaesthesia for surgical procedures 2 Month 6 Month IV 150 microgram/kg Injection
3 Endotracheal intubation and to provide muscle relaxation in general anaesthesia for surgical procedures 7 Month 12 Year IV 200 microgram/kg Injection
4 Endotracheal intubation and to provide muscle relaxation in general anaesthesia for surgical procedures over 12 Year IV infusion Injection

Ref :- Book : Martindale    Page : 2034   Edition : 38,
►  Side Effect : , tachycardia, reduction in blood pressure, reduced gastrointestinal motility, Histamine release may also lead to wheal-and-flare effects at the site of injection, flushing, occasionally bronchospasm, flushing, occasional bronchospasm,
Ref :-   Book : Martindale    Page : 2034,2030   Edition : 38,

►  Drug Interaction : Drug interaction of Mivacurium Chloride is with anticholinesterases,  NA

  ►    Mechanism of Drug Drug Interaction :  Some drugs may influence neuromuscular transmission and thus interfere with the action of both competitive and depolarising neuromuscular blockers, resulting in potentiation or antagonism of neuromuscular block. Some interactions may be advantageous, such as the reversal of competitive neuromuscular block by anticholinesterases. In general, adverse interactions are potentially more serious in patients with impaired neuromuscular function. ,
Ref :-   Book : Martindale    Page : 2035,2031   Edition : 38,


►  Contraindication : in patients with plasma cholinesterase deficiency, since its duration of action will be prolonged in such patients.,
Ref :-   Book : Martindale    Page : 2034   Edition : 38,
  ►  Mechanism of Action :   It act by competing with acetylcholine for receptors on the motor end-plate of the neuromuscular junction to produce blockade.,
Ref :-   Book : Martindale    Page : 2034,2030   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Poppy seed with Another pathway,

  ►  Pathway with its reference as follows :-
  • skeletal muscle relaxant . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Renal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 2035   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA