Mupirocin is a Medicine belongs to Antimicrobial group whose information about Brand can be referenced from   Book : Martindale    Page : 328   Edition : 38  

  ►   Brandname : Bactroban, Brodisym, Mpower, Mu-Oint, Mufect, Centany
  ►  Strength : Ointment with 2 %.  Cream with 2 %. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 898   Edition : 37   Basic & Clinical pharmacology    Page : 898   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical
Reference :-   Book : Martindale    Page : 327   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Bacterial skin infections Topical 2 % Ointment t.i.d. For up to 10 days.
2 Eradication of the nasal carriage Topical 2 % Nasal ointment b.d/t.i.d For maximum 7 days.

Ref :-  Book : Martindale    Page : 327   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
►  Side Effect : Local reactions, Burning , Stinging, Itching
Ref :-   Book : Martindale    Page : 327   Edition : 38.  

►  Drug Interaction : Drug interaction of Mupirocin is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Caution in patients with extensive burns or wounds
Ref :-   Book : Martindale    Page : 327   Edition : 38.  
  ►  Mechanism of Action :   Inhibits bacterial protein synthesis by reversible binding and inhibition of isoleucyl tRNA synthetase.
Ref :-   Book : Goodman    Page : 1544   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Adiantum capillus i.e. Samalpatti with Another pathway.   Alhagi pseudalhagi with Another pathway.   Anchusa italica with Another pathway.   Cordia latifolia i.e.Lasorda with Another pathway.   Euphorbia humifura with Another pathway.   Euphorbia maculata with Another pathway.   Foeniculum vulgare i.e. fennel with Another pathway.   Glycyrrhiza uralensis with Another pathway.   lavender with Another pathway.   Lemon balm with Another pathway.   Zizipus jujuba i.e. Indian date with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Samalpatti inhibiting bacterial protein & rna synthesis .i --- ( Pham, James S. "Aminoacyl-Trna Synthetases As Drug Targets In Eukaryotic Parasites". Int j Parasitol Drug drug Resist 4.1 (2014): 1 13. Web. 28 Jan. 2017. )
  • Alhagi pseudalhagi inhibiting bacterial protein & rna synthesis .i --- (Pham, James S. "Aminoacyl-Trna Synthetases As Drug Targets In Eukaryotic Parasites". Int j Parasitol Drug drug Resist 4.1 (2014): 1 13. Web. 28 Jan. 2017. )

  •   ►  URL --
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940080/ .
  • /www.ncbi.nlm.nih.gov/pmc/articles/PMC3798917/ .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- IRON with Dietary Substance is Drug Inhibitor.  

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20


    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal
    Ref :-   Book : Martindale    Page : 328   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA