Mycophenolate mofetil is a Medicine belongs to Immunosuppressants group whose information about Brand can be referenced from   Book : Martindale    Page : 2001   Edition : 37,

  ►   Brandname : Cellmune,Mycept,CellCept,Myfortic

  ►  Strength : Capsule with 250  mg, Tablet with 500  mg, Powder with 200  mg, Tablet with 180  mg, Tablet with 360  mg, Injection with 500  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 999   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV,
Reference :-   Book : Martindale    Page : 1999   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Acute renal graft rejection Oral 1 gm Tablet (Enteric Coated) b.d. Within 72 hours of transplantation.
2 Acute renal graft rejection IV infusion 1 gm Injection b.d. Within 24 hours after transplantation.
3 Cardiac graft rejection Oral 1.5 gm b.d. Within 5 days after transplantation.
4 Hepatic transplantation IV infusion 1 gm Injection b.d. For the first 4 days after transplantation.
5 Hepatic transplantation Oral 1.5 gm b.d.

Ref :-  Book : Martindale    Page : 1961   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Renal graft rejection 18 Year Oral 600 mg/m2 b.d.
2 Hepatic transplantation 1 Month 18 Year Oral 10 mg/kg b.d.
3 Hepatic transplantation 1 Month 18 Year IV infusion 10 mg/kg Injection b.d.

Ref :- Book : Martindale    Page : 1961   Edition : 38,
►  Side Effect : gastrointestinal disturbance, diarrhea, vomiting, gastrointestinal haemorrhage, perforation, leucopenia, risk of skin cancer, thrombocytopenia, anaemia, aplastic anaemia, bone marrow depression,
Ref :-   Book : Martindale    Page : 1996   Edition : 37,

►  Drug Interaction : Drug interaction of Mycophenolate mofetil is with Sildenafil , Xylitol , Sevelamer , Cholestyramine , Mycophenolate mofetil , Rifampicin ,
Ref :-   Book : Martindale    Page : 1996   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Mycophenolate may compete with other drugs that undergo active renal tubular secretion, resulting in increased concentrations of either drug.,
Ref :-   Book : Martindale    Page : 1996   Edition : 37,


►  Contraindication : Hypersensitivity,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 803   Edition : 3,
  ►  Mechanism of Action :   Mycophenolate mofetil a semisynthetic DMARD , is converted to mycophenolic acid the active form of the drug. The active product inhibit inosine monophosphate dehydrogenase leading to suppression of T and B lymphocyte proliferation,
Ref :-   Book : Basic & Clinical pharmacology    Page : 645   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Tulsi with Another pathway,

  ►  Pathway with its reference as follows :-
  • Eugenol is Immunomodulatory agent --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- POTASSIUM with Increase the risk of hyperkalemia ,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 1999   Edition : 37,


    ►    Plasma Half-life :   Min value :-   17.9 hour,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1966   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
    Ref :-   Book :    Page :    Edition : ,