Olmesartan medoxomil is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1459   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Olmetec,Benicar; Olmax; Olmecip; Olmefast,Olvance

  ►  Strength : Tablet with 5  mg, Tablet with 20  mg, Tablet with 40  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 224   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1459   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 20 mg Tablet o.d.

Ref :-  Book : Martindale    Page : 1494   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 hypertension 6 Year 16 Year under 35 kg Oral 10 mg Tablet o.d.
2 hypertension 6 Year 16 Year 35 and over 35 kg Oral 20 mg Tablet o.d.

Ref :- Book : Martindale    Page : 1459   Edition : 38,
►  Side Effect : Orthostatic hypotension, hypotension, Dizziness, headache, Urticaria, pruritus, angioedema, raised liver enzyme values, hypokalaemia, myalgia, arthralgia, respiratory-tract disorders, back pain, gastrointestinal disturbance, neutropenia, rhabdomyolysis,
Ref :-   Book : Martindale    Page : 1459,1424   Edition : 38,

►  Drug Interaction : Drug interaction of Olmesartan medoxomil is with , Potassium -Sparing Diuretics , , NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, ,  NA

  ►    Mechanism of Drug Drug Interaction :  An additive hyperkalaemic effect is possible with potassium supplements, potassium-sparing diuretics, or other drugs that can cause hyperkalaemia; Olmesartan medoxomil and potassium-sparing diuretics should not generally be given together. NSAIDs should be used with caution in patients taking Olmesartan medoxomil as the risk of renal impairment may be increased, particularly in those who are inadequately hydrated; use of NSAIDs may also attenuate the hypotensive effect of Olmesartan medoxomil . Olmesartan medoxomil and some other angiotensin II receptor antagonists are metabolised by cytochrome P450 isoenzymes and interactions may occur with drugs that affect these enzymes.,
Ref :-   Book : Martindale    Page : 1459,1424   Edition : 38,


►  Contraindication : Pregnancy, Severe hepatic impairment, Renal artery stenosis, renal impairment,
Ref :-   Book : Martindale    Page : 1459,1424   Edition : 38,
  ►  Mechanism of Action :   Olmesartan medoxomil is an angiotensin II receptor antagonist with antihypertensive activity due mainly to selective blockade of AT1 receptors and the consequent reduced pressor effect of angiotensin II.,
Ref :-   Book : Martindale    Page : 1459,1422   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Biliary, Renal,
Ref :-   Book : Martindale    Page : 1459   Edition : 38,


►    Plasma Half-life :
  Min value :-   10 ,    Max value :-   15 hours,
Ref :-   Book : Martindale    Page : 1459   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   1 ,    Max value :-   2 hours,
Ref :-   Book : Martindale    Page : 1459   Edition : 38,