Oseltamivir is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 1006   Edition : 38,

  ►   Brandname : Fluvir,Tamiflu,Fluvir,Tamiflu

  ►  Strength : Capsule with 75  mg, Suspension with 12  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1006   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Influenza A Oral 75 mg Capsule b.d. For 5 days.
2 Influenza B Oral 75 mg Capsule b.d. For 5 days.
3 Postexposure prophylaxis Oral 75 mg Capsule o.d. For at least 10 days and for up to 6 weeks during an epidemic.

Ref :-  Book : Martindale    Page : 1006   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Influenza A 1 Year <1 Year < 40 kg Oral 75 mg Capsule o.d.
2 Influenza A 1 Year <1 Year < 23 kg to 40 kg Oral 60 mg Capsule o.d.
3 Influenza A 1 Year <1 Year < 15 kg to 23 kg Oral 45 mg Capsule o.d.
4 Influenza A 1 Year <1 Year > 15 kg to 15 kg Oral 30 mg Capsule o.d.
5 Influenza B 1 Year <1 Year < 40 kg Oral 75 mg Capsule o.d.
6 Influenza B 1 Year <1 Year 23 to 40 kg Oral 60 mg Capsule o.d.
7 Influenza B 1 Year <1 Year < 15 kg to 23 kg Oral 45 mg Capsule o.d.
8 Influenza B 1 Year <1 Year > 15 kg to 15 kg Oral 30 mg Capsule o.d.

Ref :- Book : Martindale    Page : 1006   Edition : 38,
►  Side Effect : nausea, abdominal discomfort, local irritation, rash, delirium,
Ref :-   Book : Goodman    Page : 1607,1608   Edition : 12,

►  Drug Interaction : Drug interaction of Oseltamivir is with Fluticasone ,
Ref :-   Book : Martindale    Page : 1006   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Oseltamivir may potentially inhibit replication of the influenza virus in live influenza virus vaccines. Therefore, US licensed product information states that live influenza virus vaccines should not be given until 48 hours after stopping oseltamivir and that oseltamivir should not be given for 2 weeks after live influenza virus vaccines have been given,
Ref :-   Book : Martindale    Page : 1006   Edition : 38,


►  Contraindication : Creatinine clearance below 30 ml/minute,
Ref :-   Book : Martindale    Page : 1006   Edition : 38,
  ►  Mechanism of Action :   The neuramindidase inhibitor oseltamivir, analog of sialic acid, interfere with release of progeny influenza virus form infected host cells, thus halting the spread of infection within the respiratory tract. It competitively and reversibly interact with the active enzyme site to inhibit viral neuraminidase activity.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 886   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Tulsi with Another pathway, Thyme with Another pathway, Oregano with Another pathway, Rosemary with Another pathway, Parsley with Another pathway, Quercetin with Another pathway, Chammomila with Another pathway, Ginger (Zingiber officinale) with Another pathway, Ginger (Zingiber officinale) with Another pathway, Garlic with Another pathway, Amla with Another pathway, Amla with Another pathway, Giloy with , Mulathi with Another pathway, Kalmegha with Another pathway, Ashwagandha with Another pathway, Turmeric with Another pathway, Neem with Another pathway, Beal with Another pathway, Ajowan seed i.e . Ajwain seed with Another pathway, Ajowan seed i.e . Ajwain seed with Another pathway, Mentha with Another pathway, Green tea with Another pathway, Camphor tree with Another pathway, Eucalyptus oil with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti-Viral effect --- (duke, j. (2002). handbook of medicinal herbs (2nd ed.). united states of america: crc press. )
  • Thyme rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Oregano rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Rosemary rich in apigenin enhance the antiviral activity of aciclovir . --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Parsley rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Quercetin enhance the antiviral activity of aciclovir --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Chammomila rich in apigenin enhance the antiviral activity of aciclovir --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • anti-nausea and antiinflammatory properties --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • anti-nausea and antiinflammatory properties --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • anti-nausea and antiinflammatory properties --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • anti-nausea and antiinflammatory properties --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Garlic having active constituent ajoene act as anti-inflammatory antiviral, antibacterial, and immune‐boosting properties --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anti viral activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anti viral activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anti viral activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anti viral activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • tinosporone, tinosporic acid, syringe, alkaloid, berberine, Giloin, crude Giloininand having Anti-periodic, Anti-pyretic, Alterative, Diuretic, Antiinflammatory properties --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Glycyrrhizic acid, glycosides, coumarin, and cinnamic acid having antiviral activity anti‐inflammatory, antioxidant, and immune‐modulating activities --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Andrographolide having anti‐inflammatory, antipyretic (anti‐fever), antiviral, and immunostimulatory properties --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anaferine, anahygrine, betasisterol,Stimulant for the immune system, also a very potent adaptogen. --- (2. Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Curcumin having antiviral property --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • azadirachtin having antidiabetic, antibacterial, and antiviral properties. --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • alkaloids, coumarins, and steroids having analgesic, anti-inflammatory, antibacterial, and antiviral properties --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • phenols, thymol, carvacrol having antiseptic, antispasmodic activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • phenols, thymol, carvacrol having antiseptic, antispasmodic activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • phenols, thymol, carvacrol having antiseptic, antispasmodic activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • phenols, thymol, carvacrol having antiseptic, antispasmodic activity --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Menthol, menthone, flavonoids, carotenes, tocopherols, betaine, and choline having antimicrobial and antiviral activity --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Catechin, epicatechin having antioxidative, antiinflammatory, anticarcinogenic. --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • antiviral property --- (Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )
  • Anti viral activity --- ( Shah A. Swine Flu and Its Herbal Remedies. The International Journal Of Engineering And Science (IJES). 2013;2(5):68-78. )

  •   ►  URL -- https://books.google.co.in/books?id=B_XLBQAAQBAJ&pg=PP5&lpg=PP5&dq=duke, +j.+%282002%29.+handbook+of+medicinal+herbs+%282nd+ed.%29.+united+states+of+america:+crc+press.&source=bl&ots=iMxNGW--4H&sig=qvOrL9t7aGNOPO5wGw7_WFJ8Rjw&hl=en&sa=X&ved=0ahUKEwik4PyIpKzOAhXH0xoKHUetAogQ6AEIODAE#v=onepage&q=duke%2C%20j.%20%282002%29.%20handbook%20of%20medicinal%20herbs%20%282nd%20ed.%29.%20united%20states%20of%20america%3A%20crc%20press.&f=false, https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20, http://www.theijes.com/papers/v2-i5/Part.1/H0251068078.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 1006   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   1 hours,    Max value :-   3 hours,
    Ref :-   Book : Goodman    Page : 1006   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   2.5 hours,    Max value :-   5 hours,
    Ref :-   Book : Goodman    Page : 1607   Edition : 12,