Oxaliplatin is a Medicine belongs to Antineoplastic group whose information about Brand can be referenced from   Book : Martindale    Page : 833   Edition : 37,

  ►   Brandname : Dacotin,Eloxatin

  ►  Strength : Injection with 50  mg, Injection with 100  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 833   Edition : 12, Martindale    Page : 833   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 833   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Metastatic colorectal cancer IV infusion 85 mg/m2 Injection Over 2 to 6 hours.

Ref :-  Book : Martindale    Page : 838   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : peripheral neuropathies, progressive sensory neurotoxicity, dysesthesias, ataxia, numbness of the extremities,
Ref :-   Book : Martindale    Page : 833   Edition : 37,

►  Drug Interaction : Drug interaction of Oxaliplatin is with Fluorouracil ,
Ref :-   Book : Martindale    Page : 833   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Oxaliplatin, when is given with fluorouracil causes an increase in toxicity correlated with raised fluorouracil concentrations. The mechanism of this interaction is unclear.,
Ref :-   Book : Martindale    Page : 833   Edition : 37,


►  Contraindication : Myelosuppression, renal impairment, sensory neuropathies,
Ref :-   Book : Martindale    Page : 833   Edition : 37,
  ►  Mechanism of Action :   Oxaliplatin is a platinum-containing complex similar to cisplatin. Stimulation of the host immune response against the tumer.,
Ref :-   Book : Martindale    Page : 833   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Angeer with Another pathway,

  ►  Pathway with its reference as follows :-
  • 6-o-acyl-beta-d-glucosyl-beta-sitosterols.found in fig or anjeer have anticancer property. --- (Joseph, Baby. "Pharmacognostic And Phytochemical Properties Of Ficus Carica Linn –An Overview". International Journal of PharmTech Research 3.1 (2017): 08-12,. Print. )

  •   ►  URL -- http://sphinxsai.com/Vol.3No.1/pharm_jan-mar11/pdf/JM11(%20PT=03)%2008-12.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 833   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   0.25 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 833   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
    Ref :-   Book :    Page :    Edition : ,