Oxybutynin is a Medicine belongs to Urinary disorder group whose information about Brand can be referenced from   Book : Martindale    Page : 2394   Edition : 37,

  ►   Brandname : Ditropan,Oxyspas,Oxytrol

  ►  Strength : Tablet with 5  mg, Tablet with 10  mg, Syrup with 5  mg/ml, Gel with 10  %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 127   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, Topical,
Reference :-   Book : Martindale    Page : 2394   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Neurogenic bladder disorder Oral 5 mg Tablet b.d/t.i.d
2 Idiopathic detrusor instability Oral 5 mg Tablet b.d.
3 Overactive bladder syndrome Topical 100 mg Gel o.d.

Ref :-  Book : Martindale    Page : 2394   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Neurogenic bladder disorder 5 Year 12 Year Oral 2.5 3 mg Tablet b.d.
2 Neurogenic bladder disorder 5 Year 12 Year Oral 5 mg Tablet o.d.
3 Neurogenic bladder disorder 2 Year 5 Year Oral 1.25 2.5 mg Tablet b.d/t.i.d

Ref :- Book : Martindale    Page : 2394   Edition : 37,
Precaution :- If a Patient is using 'Oxybutynin' drug in  GALACTOCOELE  disease, then Please increases acid reflux .

►  Side Effect : Dryness of the mouth, difficulty in swallowing, reduced bronchial secretions, dilated pupils, cycloplegia, photophobia, flushing, dryness of the skin, transient bradycardia, tachycardia, palpitations, arrhythmia, difficulty in micturition, hyperthermia, hypertension, increased respiratory rate, nausea, vomiting, difficulty in thirst, difficulty in talking, mydriasis,
Ref :-   Book : Martindale    Page : 1343   Edition : 37,

►  Drug Interaction : Drug interaction of Oxybutynin is with Amantadine , Phenothiazine, , Cisapride , Domperidone , Metoclopramide ,
Ref :-   Book : Martindale    Page : 1343,1344   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  antimuscarinics may be enhanced by use with other drugs having antimuscarinic properties, such as amantadine, some antihistamines, phenothiazine antipsychotics, and tricyclic antidepressants. Inhibition of drug-metabolising enzymes by MAOIs may possibly enhance the effects of antimuscarinics. The reduction in gastric motility caused by antimuscarinics may affect the absorption of other drugs. Antimuscarinics may also antagonise the gastrointestinal effects of cisapride, domperidone, and metoclopramide.,
Ref :-   Book : Martindale    Page : 1343   Edition : 37,


►  Contraindication : prostatic enlargement, paralytic ileus, angle -closure glucoma, narrow-angle glaucoma,
Ref :-   Book : Martindale    Page : 1343   Edition : 37,
  ►  Mechanism of Action :   Oxybutynin hydrochloride is a tertiary amine antimuscarinic, it also has direct effects on smooth muscle.,
Ref :-   Book : Martindale    Page : 2394   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Buchu i.e.Barosma betulina with Another pathway,

  ►  Pathway with its reference as follows :-
  • Diuretic property --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- ALCOHOL with Alcoholic beverages while taking oxybutynin may enhance the drowsiness caused by the drug .,

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,

    ►   Route of Elimination :   Fecal, Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 2394   Edition : 37,


    ►    Plasma Half-life :   Min value :-   2 hours,    Max value :-   3 hours,
    Ref :-   Book : Martindale    Page : 2394   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 2394   Edition : 37,