Pancreatin is a Medicine belongs to group whose information about Brand can be referenced from   Book :    Page :   Edition :    Martindale    Page : 2581   Edition : 38  

  ►   Brandname : Digeplex, Biopank, Creon, Dygase, Clen-Zym, Helopan
  ►  Strength : Tablet with .  granules with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2582   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 2580   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Given in conditions of pancreatic exocrine deficiency such as pancreatitis and cystic fibrosis Oral The dose of pancreatic enzymes is adjusted according to the needs of the individual patient and will also depend on the dosage form. Doses providing up to 40 000 USP units of lipase activity may be given with each meal. So-called high-strength or high potency preparations are available for those receiving high doses, and typically contain about 20 000 to 40 000 units of lipase activity per dose unit, but their use has been associated with the development of fibrosing colonopathy in children with cystic fibrosis.

Ref :-  Book : Martindale    Page : 2580   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Abdominal discomfort, Nausea, Vomiting, Buccal and perianal irritation, particularly in infants, Colonic strictures (fibrosing colonopathy) have occurred, in children with cystic fibrosis receiving high doses of pancreatin preparations, Hypersensitivity reactions, These may be sneezing, Lachrymation, Skin rashes, Hyperuricaemia, Or hyperuricosuria have occurred with high doses, Occasional reports of the contamination of pancreatin preparations with Salmonella spp.
Ref :-   Book : Martindale    Page : 2581   Edition : 38.  

►  Drug Interaction : Drug interaction of Pancreatin is with NA

  ►    Mechanism of Drug Drug Interaction : 
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Use of high doses in patients with cystic fibrosis should be avoided
Ref :-   Book : Martindale    Page : 2581   Edition : 38.  
  ►  Mechanism of Action :   Pancreatic enzymes (as pancreatin or pancrelipase) hydrolyse fats to glycerol and fatty acids, break down protein into peptides, proteoses and derived substances, and convert starch into dextrins and sugars.
Ref :-   Book : Martindale    Page : 2580   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA