Pancuronium is a Medicine belongs to Neuromuscular blocking drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2072   Edition : 37,

  ►   Brandname : Panconium

  ►  Strength : Injection with 2  mg/ml, Injection with 1  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 2071   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Endotracheal intubation IV 50 100 micrograms/kg Injection
2 Patients who require assisted ventilation IV 60 micrograms/kg Injection Patients under intensive care who require assisted ventilation for conditions such as intractable status asthmaticus or tetanus are given drug every 1 to 1.5 hours or less frequently.

Ref :-  Book : Martindale    Page : 2071   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Endotracheal intubation >1 Day >28 Day 30 40 micrograms/kg

Ref :- Book : Martindale    Page : 2071   Edition : 37,
Precaution :- If a Patient is using 'Pancuronium' drug in  MYASTHENIA GRAVIS  disease, then Please Use with caution .

►  Side Effect : tachycardia, hypertension, bradycardia, bronchospasm, hypotension, cardiovascular collapse, excessive salivation,
Ref :-   Book : Martindale    Page : 2071   Edition : 37,

►  Drug Interaction : Drug interaction of Pancuronium is with Lidocaine , Procainamide , Quinidine , Verapamil , Paracetamol , Clindamycin , Lincomycin, Colistin, Polymyxin B, Azlocillin, Edrophonium, Galantamine hydrobromide , Neostigmine , Pyridostigmine , Rivastigmine , Carbamazapine , Phenytoin , Tamoxifen citrate , trimethaphan, Ketamine ,
Ref :-   Book : Martindale    Page : 2066,2071   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Local anesthetics :Lidocaine, procainamide, quinidine, and verapamil all have some neuromuscular blocking activity and may enhance the block produced by neuromuscular blockers. .2 Some antibacterials in very high concentration can produce a muscle paralysis that may be additive to or synergistic with that produced by neuromuscular blockers.3. Anticholinesterases, including ecothiopate, edrophonium, galantamine, neostigmine, pyridostigmine, rivastigmine, and possibly donepezil, antagonise the effect of competitive neuromuscular blockers.,
Ref :-   Book : Martindale    Page : 2066,2071   Edition : 37,


►  Contraindication : renal impairment, respiratory insufficiency or pulmonary disease , asthma,
Ref :-   Book : Martindale    Page : 2066   Edition : 37,
  ►  Mechanism of Action :   Pancuronium has vagolytic and sympathomimetic action, which may cause tachycardia and hypertension, but does not produce ganglionic blockade.,
Ref :-   Book : Goodman    Page : 262   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal,
Ref :-   Book : Martindale    Page : 2071   Edition : 37,


►    Plasma Half-life :
  Min value :-   2 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 2071   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,