Papaverine is a Medicine belongs to Urological drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2363   Edition : 38  

  ►   Brandname : Paparin

  ►  Strength : Tablet with .  Injection with . 

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2363   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, IV
Reference :-   Book : Martindale    Page : 2395   Edition : 37  


Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Erectile dysfunction intracavernosal injection 2.5 60 mg Injection Injected into the corpus cavernosum of the penis. Dose must be initially titrated by the prescriber. Doses up to about 30 mg have been combined with phentolamine.

Ref :-  Book : Martindale    Page : 2362   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Gastrointestinal disturbance, Flushing of the face, Headache, Malaise, Drowsiness, Skin rashes, Sweating, Orthostatic hypotension, Dizziness, Jaundice, Eosinophilia, Altered liver function tests, Hypersenstivity
Ref :-   Book : Martindale    Page : 2395   Edition : 37.  

►  Drug Interaction : Drug interaction of Papaverine is with ,  NA


  ►    Mechanism of Drug Drug Interaction : 
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Intravenous dosage is contra-indicated in patients with complete AV block.
Ref :-   Book : Martindale    Page : 2362   Edition : 38.  
  ►  Mechanism of Action :   Papaverine has a direct relaxant effect on smooth muscle which is attributed in part to its ability to inhibit phosphodiesterase.
Ref :-   Book : Martindale    Page : 2362   Edition : 38.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions

​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal
Ref :-   Book : Martindale    Page : 2395   Edition : 37.  

►    Plasma Half-life :   Min value :-   After Oral dose; 1,    Max value :-   2 hours.  
Ref :-   Book : Martindale    Page : 2363   Edition : 38.  

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA