Paromomycin is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 944   Edition : 38,

  ►   Brandname : Humatin

  ►  Strength : Capsule with 250  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 935   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM,
Reference :-   Book : Martindale    Page : 944   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Intestinal amoebiasis Oral 25 35 mg/kg Capsule Daily in 3 divided doses with meals for 5 to 10 days.
2 Taeniasis and other tapeworm infections Oral 4 gm Capsule Given as a single dose or in divided doses over the course of one hour.
3 Hepatic amoebiasis Oral 4 gm Given daily in divided oral doses at regular intervals for 5 to 6 days.

Ref :-  Book : Martindale    Page : 944   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Intestinal amoebiasis Oral 25 35 mg/kg Syrup
2 Intestinal amoebiasis <5 IM 11 mg/kg Injection

Ref :- Book : Martindale    Page : 944   Edition : 38,
►  Side Effect : mild injection pain, occasional abdominal distress, reversible liver enzyme elevations, diarrhea, nephrotoxicity, ototoxicity,
Ref :-   Book : Goodman    Page : 1433   Edition : 12, Goodman    Page : 1433, 1434   Edition : 12, Goodman    Page : 1433,1434   Edition : 12,

►  Drug Interaction : Drug interaction of Paromomycin is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Hypersensitivity,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 596   Edition : 3,
  ►  Mechanism of Action :   This is an irreversable inhibitor of protein synthesis. It binds to specific 30S subunit ribosomal protein. Protein synthesis is inhibited by interference with initiation complex of peptide formation, misreading of m-RNA and breakup of polysomes into non funtional monosomes,
Ref :-   Book : Goodman    Page : 1507   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Red algae with Another pathway,

  ►  Pathway with its reference as follows :-
  • Antibiotic effect --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 944   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   2.62 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 944   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   0.5 hours,    Max value :-   1.5 hours,
    Ref :-   Book : Martindale    Page : 944   Edition : 38,