Paromomycin is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 944   Edition : 38, Martindale    Page : 944   Edition : 38,

  ►   Brandname : Humatin,Ameparomo

  ►  Strength : Capsule with 250  mg, Syrup with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 935   Edition : 12, Martindale    Page : 944   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM,
Reference :-   Book : Martindale    Page : 944   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Intestinal amoebiasis Oral 25 35 mg/kg Capsule Daily in 3 divided doses with meals for 5 to 10 days.
2 Taeniasis and other tapeworm infections Oral 4 gm Capsule Given as a single dose or in divided doses over the course of one hour.
3 Hepatic coma Oral 4 gm Given daily in divided doses at regular intervals for 5 to 6 days.

Ref :-  Book : Martindale    Page : 944   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Intestinal amoebiasis Oral 25 35 mg/kg Syrup
2 Visceral Leishmaniasis more than 5 kg IM 11 mg/kg Injection

Ref :- Book : Martindale    Page : 944   Edition : 38,
►  Side Effect : Serious adverse effects are, neuromuscular blockade, ototoxicity, Acute renal failure,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 596   Edition : 3,

►  Drug Interaction : Drug interaction of Paromomycin is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Hypersensitivity,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 596   Edition : 3,
  ►  Mechanism of Action :   Aminoglycosides bind to polysomes and interfere with protein synthesis by causing misreading and premature termination of mRNA translation. The primary intracellular site of action of the aminoglycosides is the 30S ribosomal subunit, which consists of 21 proteins and a single 16S molecule of RNA.,
Ref :-   Book : Goodman    Page : 1507   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Red algae with Another pathway,

  ►  Pathway with its reference as follows :-
  • Antibiotic effect --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy, +C.+K.+Kokate, +A.P.+Purohit, +S.B.+Gokhale,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 944   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   2.62 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 944   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   0.5 hours,    Max value :-   1.5 hours,
    Ref :-   Book : Martindale    Page : 944   Edition : 38,