Pefloxacin is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 338   Edition : 38  

  ►   Brandname : Pelox, Proflox, Qucin, Beining
  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV
Reference :-   Book : Martindale    Page : 341   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Gonococcal urethritis Oral 800 mg A single dose given to men.
2 Acute uncomplicated cystitis Oral 800 mg A single dose given to women.

Ref :-  Book : Martindale    Page : 341   Edition : 37  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Gastrointestinal disturbances, Include, Nausea, Vomiting, Diarrhea, Abdominal pain, Dyspepsia, Are the most frequent adverse effects, Headache, Dizziness, Confusion, Insomnia, Restlessness, Are the commonest effects on the CNS, Rashes, pruritus, Photosensitivity, Anaphylaxis, Adverse effects on the musculoskeletal system has led to restrictions in some countries, Reversible arthralgia, Or myalgia, Joint erosions, Muscle weakness may be exacerbated in patients with myasthenia gravis
Ref :-   Book : Martindale    Page : 262,338   Edition : 38.  

►  Drug Interaction : Drug interaction of Pefloxacin is with NA

  ►    Mechanism of Drug Drug Interaction : 
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Pregnant and lactating women, G6PD deficiency, Renal impairment, Epilepsy, Myasthenia gravis
Ref :-   Book : Martindale    Page : 264,338   Edition : 38.  
  ►  Mechanism of Action :   The quinolone antibiotics target bacterial DNA gyrase and topoisomerase IV. For many gram-positive bacteria (such as S. aureus), topoisomerase IV is the primary activity inhibited by the quinolones. In contrast, DNA gyrase is the primary quinolone target in many gram-negative microbes (such as E. coli)
Ref :-   Book : Goodman    Page : 1470   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism)
Ref :-   Book : Martindale    Page : 341   Edition : 38.  

►    Plasma Half-life :   Min value :-   about 8 ,    Max value :-   13 hours.  
Ref :-   Book : Martindale    Page : 338   Edition : 38.  

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA