Penciclovir is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 995   Edition : 37,

  ►   Brandname : Fenistil,Vectavir,Denavir

  ►  Strength : Cream with 1  %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical, Oral,
Reference :-   Book : Martindale    Page : 996   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Herpes labialis Topical 1 % Cream Applied as cream every 2 hours during waking hours for 4 days.

Ref :-  Book : Martindale    Page : 996   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Primary or recurrent herpes labialis >2 Year Topical 1 % Cream
2 Herpes simplex infections of the skin >2 Year Topical 1 % Cream

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1069   Edition : 19,
►  Side Effect : transitory stinging, burning , Numbness,
Ref :-   Book : Martindale    Page : 995   Edition : 37,

►  Drug Interaction : Drug interaction of Penciclovir is with Probenecid ,
Ref :-   Book : Martindale    Page : 995   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Plasma concentrations of penciclovir may be increased in patients receiving probenecid with the prodrug famciclovir.,
Ref :-   Book : Martindale    Page : 901   Edition : 36,


►  Contraindication : Hypersensitivity,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 670   Edition : 3,
  ►  Mechanism of Action :   It phosphorylated by viral kinases and then inhibit viral DNA polymerase.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 670   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Guduchi with ,

  ►  Pathway with its reference as follows :-
  • Arabinogalactan have antiviral effect --- ( Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 996   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 996   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   0.75 hours,    Max value :-   1 hours,
    Ref :-   Book : Martindale    Page : 996   Edition : 37,