Pentazocine is a Medicine belongs to Analgesic opoids group whose information about Brand can be referenced from   Book : Martindale    Page : 118   Edition : 37,

  ►   Brandname : Fortral,Talwin NX

  ►  Strength : Injection with 30  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 562   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, SC, IM, IV, rectal, sublingual,
Reference :-   Book : Martindale    Page : 341   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Labour pain IM 30 mg Injection Given as a single dose during labour.

Ref :-  Book : Martindale    Page : 117,118   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, constipation, drowsiness, Confusion, dry mouth, Dizziness, sweating, facial flushing, headache, vertigo, bradycardia, tachycardia, palpitations, Orthostatic hypotension, hypothermia, Restlessness, changes of mood, decreased libido, hallucinations, Miosis, agranulocytosis, skin reaction, erythema multiforme, toxic epidermal necrolysis, local tissue damage,
Ref :-   Book : Martindale    Page : 106, 117   Edition : 37, Martindale    Page : 106,117   Edition : 37,

►  Drug Interaction : Drug interaction of Pentazocine is with Mexiletine , Cisapride , Metoclopramide , Domperidone , Ciprofloxacin , Zonisamide , Oxcarbazepine ,
Ref :-   Book : Martindale    Page : 107,117   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  The actions of opioids may in turn affect the activities of other drugs. For instance, their gastrointestinal effects may delay absorption as with mexiletine or may be counteractive as with cisapride, metoclopramide, or domperidone. Opioid premedicants such as papaveretum have been reported to reduce serum concentrations of ciprofloxacin,
Ref :-   Book : Martindale    Page : 107   Edition : 37,


►  Contraindication : respiratory depression, Obstructive airway disease, Acute alcoholism, convulsive disorders, head injury, myocardial infraction, heart failure, pulmonary hypertension,
Ref :-   Book : Martindale    Page : 107,117   Edition : 37,
  ►  Mechanism of Action :   Pentazocine, a benzomorphan derivative, is an opioid analgesic that has mixed opioid agonist and antagonist actions. Agonist activity is thought to be mainly at κ opioid receptors (with possibly some σ receptor activity); it acts as a weak antagonist or partial agonist at μ receptors.,
Ref :-   Book : Martindale    Page : 117   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal,
Ref :-   Book : Martindale    Page : 117   Edition : 37,


►    Plasma Half-life :
  Min value :-   2 hours,    Max value :-   3 hours,
Ref :-   Book : Martindale    Page : 117   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   3 hours,
Ref :-   Book : Martindale    Page : 117   Edition : 37,