Phenoxybenzamine is a Medicine belongs to Adrenoceptor blockers group whose information about Brand can be referenced from   Book : Martindale    Page : 1504   Edition : 37,

  ►   Brandname : Fenoxene,Dibenzyline

  ►  Strength : Capsule with 10  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 166   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV,
Reference :-   Book : Martindale    Page : 1504   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Phaeochromocytoma Oral 10 mg Capsule o.d/b.d
2 Phaeochromocytoma IV infusion 1 mg/kg Injection Given daily; In 200 mL of sodium chloride 0.9% infused over at least 2 hours.
3 Urinary retention Oral 10 mg Capsule b.d. Due to neurogenic bladder.

Ref :-  Book : Martindale    Page : 1504   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Orthostatic hypotension, Dizziness, reflex tachycardia, nasal congestion, Miosis, dry mouth, decreased sweating, drowsiness, fatigue, Confusion, inhibition of ejaculation, convulsion,
Ref :-   Book : Martindale    Page : 1503   Edition : 37,

►  Drug Interaction : Drug interaction of Phenoxybenzamine is with Adrenaline,
Ref :-   Book : Martindale    Page : 1503   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  NA


►  Contraindication : heart failure, ischaemic heart disease, Cerebrovascular disease, renal impairment,
Ref :-   Book : Martindale    Page : 1503   Edition : 37,
  ►  Mechanism of Action :   NA

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Fish with Another pathway, Garlic with Another pathway,

  ►  Pathway with its reference as follows :-
  • Fish-EPA & DHA have Antihypertensives --- (Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart. )
  • Antihypertensives --- (Tabassum, N. & Ahmad, F. (2011). Role of natural herbs in the treatment of hypertension. Pharmacognosy Reviews, 5(9), 30. )

  •   ►  URL -- http://197.14.51.10:81/pmb/AGROALIMENTAIRE/Handbook%20of%20Nutrition.pdf, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210006/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 1503   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   24 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1503   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1503   Edition : 37,