Podophyllum resin/Podophyllum is a Medicine belongs to Dermatological drug group whose information about Brand can be referenced from   Book : Martindale    Page : 1752   Edition : 37   Martindale    Page : 1717   Edition : 38  

  ►   Brandname : Condyline, Warticon, Condylox, Wartec, Podofilm
  ►  Strength : Paint with .  Topical solution with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1717   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical
Reference :-   Book : Martindale    Page : 1752   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Anogenital warts Topical The solution is left on the warts for 1 to 6 hours, and then washed off. Only a small area or number of warts should be treated at any one time and care must be taken to avoid application to healthy tissue. This procedure is carried out once a week for up to 3 to 6 weeks. Preparations containing podophyllotoxin 0.5% in alcohol or alcoholic gel or podophyllotoxin 0.15% cream are used similarly. They are applied twice daily for 3 days but not washed off. Treatment may be repeated at weekly intervals for up to a total of 4 or 5 weeks of treatment. Podophyllum resin is also used with other keratolytics for the removal of plantar warts.

Ref :-  Book : Martindale    Page : 1717   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Very irritant, especially to the eyes and mucous membranes, Vomiting, Abdominal pain, Diarrhea, It can also cause severe systemic toxicity after ingestion or topical application, which is usually reversible but has been fatal
Ref :-   Book : Martindale    Page : 1717   Edition : 38.   Martindale    Page : 1752   Edition : 37.  

►  Drug Interaction : Drug interaction of Podophyllum resin/Podophyllum is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B.
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Pregnant and lactating women
Ref :-   Book : Martindale    Page : 1752   Edition : 37.  
  ►  Mechanism of Action :   Podophyllotoxin and its derivatives are active cytotoxic agents with specific affinity for the microtubule protein of the mitotic spindle. Normal assembly of the spindle is prevented, and epidermal mitoses are arrested in metaphase
Ref :-   Book : Basic & Clinical pharmacology    Page : 1075   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Garlic with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Components of garlic (Allium sativum) have been shown to have antiviral activity and to inhibit cellular proliferation of virally infected cells. --- ( Libke, M. (2004). An Armamentarium of Wart Treatments. Clin Med Res, 4(4), 273–293. )

  •   ►  URL --
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764803/#r67 .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA