Prussian blue/Ferric Ferrocyanide is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1573   Edition : 38  

  ►   Brandname : Radiogardase, Antidotum Thallii-Heyl
  ►  Strength : Capsule with 500 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1025   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 1603   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Radiocaesium contamination 1 or 2 gm t.i.d. Above dose given once the internal radioactivity has been substantially decreased, which may improve gastrointestinal tolerance. Dose given by mouth or by nasogastric tube. A minimum of 30 days treatment should be given.
2 Thallium poisoning The usual dose of Prussian blue is 250 to 300 mg/kg daily, or up to 20 g daily for an adult, given in divided doses either by mouth or by nasogastric or duodenal tube. Treatment should continue until the urinary excretion of thallium falls to 500 micrograms or less per 24 hours, the urine or blood concentration is less than 10 micrograms/L, or no thallium can be detected in the faeces.

Ref :-  Book : Martindale    Page : 1573   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Thallium poisoning or for known or suspected internal contamination with radiocaesium

Ref :- Book : Martindale    Page : 1573   Edition : 38  
►  Side Effect : Constipation, It may result in blue discoloration of the mouth and teeth when given orally
Ref :-   Book : Martindale    Page : 1572   Edition : 38.  

►  Drug Interaction : Drug interaction of Prussian blue/Ferric Ferrocyanide is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B.
Ref :-   Book :    Page :    Edition : .  


►  Contraindication :
Ref :-   Book :    Page :    Edition : .  
  ►  Mechanism of Action :   When given orally it forms a non-absorbable complex with thallium or caesium in the gastrointestinal tract and increases their elimination from the body; it may also bind other elements and patients should be monitored for electrolyte imbalances. Prussian blue may cause constipation and a fibre-based laxative is recommended.
Ref :-   Book : Martindale    Page : 1573   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA