Pyrantel- pamoate is a Medicine belongs to Antihelminthic Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 163   Edition : 37,

  ►   Brandname : Nemocid,Pin-Rid

  ►  Strength : Suspension with 50  mg/ml, Capsule with 62.5  Mg, Capsule with 125  mg, Capsule with 180  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 946   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 946   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Susceptible infections Oral 10 mg/kg Tablet/Capsule Given as a single dose.
2 Ascariasis Oral 5 mg Tablet/Capsule
3 Nicatoriasis Oral 2.5 mg/kg Tablet/Capsule t.i.d/q.i.d Given as a single dose.
4 Enterobiasis Oral 10 mg/kg Tablet/Capsule Daily for 3 or 4 days.
5 Trichinosis Oral 10 mg Tablet/Capsule Daily for 5 days.

Ref :-  Book : Martindale    Page : 166   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, Dizziness, drowsiness, insomnia, Skin rashes, raised liver enzyme values,
Ref :-   Book : Martindale    Page : 163   Edition : 37,

►  Drug Interaction : Drug interaction of Pyrantel- pamoate is with Piperazine ,
Ref :-   Book : Martindale    Page : 163   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  The anthelmintic effects of both pyrantel and piperazine may be antagonised when the two drugs are used together,
Ref :-   Book : Martindale    Page : 163   Edition : 37,


►  Contraindication : hepatic impairment,
Ref :-   Book : Martindale    Page : 163   Edition : 37,
  ►  Mechanism of Action :   Pyrantel and its analogs are depolarizing neuromuscular blocking agents. They open nonselective cation channels and induce persistent activation of nicotinic acetylcholine receptors and spastic paralysis of the worm. ,
Ref :-   Book : Goodman    Page : 1458   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Papaya with Another pathway,

  ►  Pathway with its reference as follows :-
  • papain have anthelmintic activity --- (Pdr For Herbal Medicine. 4th ed. 2016. Print )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pubmed/19459740,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 163   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   3 hours,
    Ref :-   Book : Basic & Clinical pharmacology    Page : 945   Edition : 37,