Quinacrine/Mepacrine Hydrochloride is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 923   Edition : 37  

  ►   Brandname : Maladi

  ►  Strength : Tablet (Extended Release Tablets) with nf . 

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 923   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 923   Edition : 37  


Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Dizziness, Headache, Gastrointestinal disturbance, Nausea, Vomiting, Reversible yellow discoloration of the skin, Conjunctiva, Blue/black discoloration of the palate, Discoloration of the nails, Transient acute toxic psychosis, Exfoliative dermatitis, Aplastic anaemia, Hepatitis, Hepatic necrosis
Ref :-   Book : Martindale    Page : 923   Edition : 37.  

►  Drug Interaction : Drug interaction of Quinacrine/Mepacrine Hydrochloride is with Zonisamide , Primaquine
Ref :-   Book : Martindale    Page : 923   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  Mepacrine has been reported to produce a mild disulfiram-like reaction when taken with alcohol. Mepacrine may increase the plasma concentrations of primaquine resulting in a higher risk of toxicity, and it has been recommended that these drugs should not be used together.
Ref :-   Book : Martindale    Page : 923   Edition : 37.  


►  Contraindication : Psychosis, Hepatic disease, Psoriasis
Ref :-   Book : Martindale    Page : 923   Edition : 37.  
  ►  Mechanism of Action :   Nf
Ref :-   Book :    Page :    Edition : .  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- Red algae with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Antibiotic effect due to Cycloeudesmol, Aeroplysinin --- (Kokate, c. & Purohit, A. (2016). pharmacognosy. nirali prakashan. )

    •   ►  URL --
  • https://www.sapnaonline.com/books/pharmacognosy-ck-kokate-8196396155-9788196396152 .
    •


    DIETARY Substance Interactions

    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance

    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal
    Ref :-   Book : Martindale    Page : 923   Edition : 37.  

    ►    Plasma Half-life :   Min value :-   120 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 923   Edition : 37.  

    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   3 hours.  
    Ref :-   Book : Martindale    Page : 923   Edition : 37.