Rabies vaccine is a Medicine belongs to vaccine group whose information about Brand can be referenced from   Book : Martindale    Page : 2444   Edition : 37,

  ►   Brandname : Rabipur,Rabivax,Imovax Rabies,RabAver

  ►  Strength : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2442   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM,
Reference :-   Book : Martindale    Page : 2442   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Pre-exposure prophylaxis IM 1 ml Injection Dose: Given in 3 doses on days 0, 7, and 28; the third dose may in some instances be given on day 21 if there is insufficient time before travel.
2 Postexposure treatment IM 1 ml Injection Dose: Given for unimmunised or incompletely immunised persons is 5 doses on days 0, 3, 7, 14, and 30. In fully immunised persons two doses of vaccine should be given intramuscularly, one each on day 0 and day 3.

Ref :-  Book : Martindale    Page : 2442   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1156   Edition : 19,
►  Side Effect : Pain, erythema, abdominal pain, diarrhea, nausea, vomiting, headache, chills, Dizziness, fever, malaise, convulsion, encephalitis, lymphadenopathy, arthralgia, myalgia, dyspnoea, wheezing, rash, hypersensitivity reactions, anaphylaxis,
Ref :-   Book : Martindale    Page : 2442   Edition : 37,

►  Drug Interaction : Drug interaction of Rabies vaccine is with Antineoplastic , Corticosteroid ,  NA

  ►    Mechanism of Drug Drug Interaction :  Vaccines to induce an immune response can be influenced by the recent use of other vaccines or immunoglobulins. Patients receiving immunosuppressant therapy, including antineoplastics or therapeutic doses of corticosteroids, may also display a reduced response to vaccines.,
Ref :-   Book : Martindale    Page : 2407,2442   Edition : 37,


►  Contraindication : , Patients known to be hypersensitive to a particular vaccine or its components should be given an alternative product if available, although there are no absolute contra-indications to postexposure treatment, Pre-exposure prophylaxis should be delayed in patients with febrile illness until fever has resolved,
Ref :-   Book :    Page :    Edition : , Martindale    Page : 2442   Edition : 37,
  ►  Mechanism of Action :   ,
Ref :-   Book :    Page :    Edition : ,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Dhatura stramonium i. e Banjii with Another pathway,

  ►  Pathway with its reference as follows :-
  • Alkaloids have Anti Rabies activity --- (PLoS Negl Trop Dis. 2015 Jun; 9(6): e0003867. Published online 2015 Jun 26. doi: 10.1371/journal.pntd.0003867 PMCID: PMC4482645 Knowledge, Attitudes and Practices of Animal Bite Victims Attending an Anti-rabies Health Center in Jimma Town, Ethiopia Tadele Kabeta,1,2 Benti Deresa,1 Worku Tigre,1 Michael P. Ward,3 and Siobhan M. Mor3,4,* Jakob Zinsstag, Editor )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482645/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA