Rimantadine Hydrochloride is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 1000   Edition : 37,

  ►   Brandname : Flumadine

  ►  Strength : Tablet with 100  mg, Syrup with 50/5  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Prophylaxis and treatment of susceptible influenza A infections Oral 200 mg Tablet Dose: Given daily in divided doses.

Ref :-  Book : Martindale    Page : 999   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Prophylaxis of influenza A 1 Year Oral 5 mg/kg Tablet
2 Prophylaxis of influenza A 10Year Oral 100 mg Tablet b.d.

Ref :- Book : Martindale    Page : 999   Edition : 37,
►  Side Effect : Gastrointestinal disturbances, nausea, vomiting, abdominal pain, dry mouth, anorexia, headache, insomnia, Nervousness, Dizziness, asthenia, ataxia, agitation, Concentration difficulties, diarrhoea, dyspepsia, Depression, dyspnoea, Skin rashes, Somnolence, tinnitus,
Ref :-   Book : Martindale    Page : 999   Edition : 37,

►  Drug Interaction : Drug interaction of Rimantadine Hydrochloride is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Severe hepatic and renal impairment, There have been reports of convulsions, including grand mal convulsions, and rimantadine should be given with caution to patients with epilepsy.,
Ref :-   Book : Martindale    Page : 999   Edition : 37,
  ►  Mechanism of Action :   Inhibit influenza A uncoating by blocking M2, a proton channel that acidifies the interior of the virus; acidification is necessary for dissociation is necessary for dissociation of viral matrix protein from the viral ribonucleoprotein.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 670   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Tulsi with Another pathway, Quercetin with Another pathway, Parsley with Another pathway, Rosemary with Another pathway, Oregano with Another pathway, Thyme with Another pathway,

  ►  Pathway with its reference as follows :-
  • eugenol have Anti viral activity. --- ( Kayastha, B. (2014). Queen of herbs tulsi ( ocimum sanctum ) removes impurities from water and plays disinfectant role. Journal Of Medicinal Plants Studies, 2(2). )
  • Quercetin enhance the antiviral activity of aciclovir --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Parsley rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Rosemary rich in apigenin enhance the antiviral activity of aciclovir . --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Oregano rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Thyme rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )

  •   ►  URL -- http://www.plantsjournal.com/vol2Issue2/Issue_feb_2014/1.3.pdf, https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   6 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 999   Edition : 37,