Roxithromycin is a Medicine belongs to MACROLIDES group whose information about Brand can be referenced from   Book : Martindale    Page : 357   Edition : 38,

  ►   Brandname : Biorox,Roxee,Roxem,Roxeptin

  ►  Strength : Tablet with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 357   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 360   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Susceptible infections Oral 150 mg b.d.
2 Susceptible infections Oral 300 mg o.d.

Ref :-  Book : Martindale    Page : 360   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Susceptible infections 6 to 40 kg Oral 5 8 mg/kg

Ref :- Book : Martindale    Page : 360   Edition : 37,
►  Side Effect : gastrointestinal disturbance, abdominal discomfort, cramp, nausea, vomiting, pruritus, Urticaria, Skin rashes, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis,
Ref :-   Book : Martindale    Page : 293   Edition : 38,

►  Drug Interaction : Drug interaction of Roxithromycin is with NA

  ►    Mechanism of Drug Drug Interaction :  Roxithromycin has a much lower affinity for cytochrome P450 isoenzymes than erythromycin and therefore has fewer interactions. It does not appear to interact with antacids, carbamazepine, oral contraceptives, prednisolone, or ranitidine.,
Ref :-   Book : Martindale    Page : 356   Edition : 38,


►  Contraindication : Hypersensitivity, Arrhythmia, prolonged QT interval , hepatic impairment, renal impairment, pregnancy,
Ref :-   Book : Martindale    Page : 294   Edition : 38,
  ►  Mechanism of Action :   It is a bacteriostatic agent that inhibit protein synthesis by binding reversibly to 50S ribosomal subunits of sensitive microorganisms, at or very near the site that binds chloramphenicol. ,
Ref :-   Book : Goodman    Page : 1530   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Fecal, Hepatic (Metabolism), lungs, Renal,
Ref :-   Book : Martindale    Page : 357   Edition : 38,


►    Plasma Half-life :
  Min value :-   8 hours,    Max value :-   18 hours,
Ref :-   Book : Martindale    Page : 357   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 359   Edition : 38,