Sodium calcium edetate is a Medicine belongs to Chelators group whose information about Brand can be referenced from   Book : Martindale    Page : 1574   Edition : 38   Martindale    Page : 1574   Edition : 38  

  ►   Brandname : Ledclair, ledcure
  ►  Strength : Injection with 200 mg/ml. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1025   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV infusion, IM
Reference :-   Book : Martindale    Page : 1573   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 SEVERE TOXICITY or Encephalopathy IV infusion 80 mg/kg Injection Daily given in two divided doses or 75 mg/kg once daily, I.V infusion over at least 1 hours.
2 SEVERE TOXICITY or Encephalopathy IV infusion 1 gm/m2 Injection Daily over 8 to 12 hours or by I.M injection is Suggested for asymptomatic patients
3 Symptomatic poisoning IM 1.5 gm/m2 Injection In divided dose may be used with Dimercaprol.

Ref :-  Book : Martindale    Page : 1573   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
►  Side Effect : Nephrotoxic, Glycosuria, Proteinuria, Haematuria, Renal proximal tubular necrosis, Thrombophlebitis, Gastrointestinal disturbance, Nausea, Diarrhoea, Abdominal pain, Chills, Fever, Malaise, Headache, Myalgia, Arthralgia, Sneezing, Nasal congestion, Lachrymation, Increase in liver enzyme values, Transient hypotension, Tremor, Numbness, Tingling, Rashes, Cardiac rhythm irregularities, Cheilosis, Anaemia, Transient bone marrow depression, Excessive thrist, Hypercalcaemia
Ref :-   Book : Martindale    Page : 1574   Edition : 38.  

►  Drug Interaction : Drug interaction of Sodium calcium edetate is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : Renal impairment, Should not be given orally in the treatment of lead poisoning
Ref :-   Book : Martindale    Page : 1604   Edition : 37.   Martindale    Page : 1574   Edition : 38.  
  ►  Mechanism of Action :   N.F.R.B
Ref :-   Book :    Page :    Edition : .  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal
Ref :-   Book : Martindale    Page : 1574   Edition : 38.  

►    Plasma Half-life :   Min value :-   20 minutes,    Max value :-   60 minutes.  
Ref :-   Book : Martindale    Page : 1574   Edition : 38.  

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA