Sodium stibogluconate (or meglumine antimonate) is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 928   Edition : 38,

  ►   Brandname : Glucantime

  ►  Strength : Injection with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 928   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM, intralesional injection,
Reference :-   Book : Martindale    Page : 927   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Visceral Leishmaniasis IM 20 mg/kg Injection For 28 days.
2 Cutaneous leishmaniasis Intralesional injections 100 300 mg Injection o.d/b.d
3 Mucocutaneous leishmaniasis IM 20 mg/kg Injection For a minimum of 4 weeks.

Ref :-  Book : Martindale    Page : 926   Edition : 38, Martindale    Page : 927   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Leishmania infection IM 20 mg/kg/day Injection
2 Leishmania infection IV 20 mg/kg/day Injection
3 Cutaneous lesion IM or IV 20 mg/kg/day Injection
4 Visceral Leishmaniasis >10 kg IM 200 mg Injection

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1189, 1190   Edition : 19, Martindale    Page : 927   Edition : 38,
►  Side Effect : fever, headache, myalgia, arthralgia, Rashes, sterile abscesses, Electrocardiographic changes, T-wave changes, QT prolongation, dangerous arrhythmias, haemolytic anaemia, serious renal, serious cardiac effects, shock, sudden death, serious liver effects, serious renal effects,
Ref :-   Book : Goodman    Page : 1436   Edition : 12,

►  Drug Interaction : Drug interaction of Sodium stibogluconate (or meglumine antimonate) is with Amphotericin B ,
Ref :-   Book : Martindale    Page : 928   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  It was suggested that sodium stibogluconate increased the susceptibility of the myocardium to damage by amphotericin B,
Ref :-   Book : Martindale    Page : 928   Edition : 38,


►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►  Mechanism of Action :   The mechanism of action of antimonials is unknown. ,
Ref :-   Book : Basic & Clinical pharmacology    Page : 933   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 928   Edition : 38,


►    Plasma Half-life :
  Min value :-   2 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 928   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,