Somatostatin is a Medicine belongs to DRUGS USED TO TREAT VARICEAL HEMORRHAGE group whose information about Brand can be referenced from   Book : Martindale    Page : 1967   Edition : 37,

  ►   Brandname : Somastin,Stilamin

  ►  Strength : Injection with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1967   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 1967   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Gastrointestinal haemorrhage IV bolus 250 mg Injection Over 3 to 5 minutes.

Ref :-  Book : Martindale    Page : 1967   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : abdominal discomfort, flushing, nausea, bradycardia,
Ref :-   Book : Martindale    Page : 1967   Edition : 37,

►  Drug Interaction : Drug interaction of Somatostatin is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►  Mechanism of Action :   Somatostatin is a polypeptide obtained from the hypothalamus or by synthesis. The naturally occurring form has a cyclic structure. Although somatostatin derived from the hypothalamus is a 14-amino-acid peptide, a longer, 28-amino-acid form also exists in some tissues. Somatostatin inhibits the release of growth hormone from the anterior pituitary. It also inhibits the release of thyrotrophin and corticotropin from the pituitary, glucagon and insulin from the pancreas, and appears to have a role in the regulation of duodenal and gastric secretions. In the CNS it appears to play a role in the perception of pain.,
Ref :-   Book : Martindale    Page : 1967   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Brazil nuts with Another pathway, Sea food with Another pathway, Fish with Another pathwayAnother pathway, Fish with Another pathwayAnother pathway,

  ►  Pathway with its reference as follows :-
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256. http://dx.doi.org/10.1136/jmg.21.4.254 )
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256. )
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256 )
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256 )
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256 )
  • selenium have growth hormone inhibiter --- (Collipp, P., Kelemen, J., Chen, S., Castro-Magana, M., Angulo, M., & Derenoncourt, A. (1984). Growth hormone inhibition causes increased selenium levels in Duchenne muscular dystrophy: a possible new approach to therapy. Journal Of Medical Genetics, 21(4), 254-256 )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1049292/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   0.033,    Max value :-   NA
    Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 530   Edition : 3,

    ►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
    Ref :-   Book :    Page :    Edition : ,