Sucralfate is a Medicine belongs to Proton pump inhibitor group whose information about Brand can be referenced from   Book : Martindale    Page : 1928   Edition : 37,

  ►   Brandname : Alfate,Sucrase,Ulcekon,Antepsin,Carafate

  ►  Strength : Tablet with 1  gm, Suspension with 1/10  gm/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1111   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1928   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Peptic ulcer Oral 1 gm Tablet q.i.d. Should be taken on an empty stomach before meals and at bedtime.
2 Chronic gastritis Oral 1 gm Tablet q.i.d.
3 Prophylaxis of gastrointestinal haemorrhage Oral 1 gm Tablet Six times daily.

Ref :-  Book : Martindale    Page : 1889   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Peptic ulcer 1 Month 2 Year Oral 250 mg Tablet
2 Peptic ulcer 2 Year 12 Year Oral 500 mg Tablet
3 Peptic ulcer 12 Year 15 Year Oral 1 gm Tablet
4 Peptic ulcer 15 Year 18 Year Oral 1 gm Tablet q.i.d.

Ref :- Book : Martindale    Page : 1889   Edition : 38,
Precaution :- If a Patient is using 'Sucralfate' drug in PEPTIC ULCER DISEASE disease, then Please should be avoided   if he ever suffered from chronic kidney disease disease.
►  Side Effect : diarrhea, nausea, vomiting, Flatulence, gastric discomfort, dry mouth, Dizziness, headache, vertigo, back pain, Skin rashes, pruritus, hypersensitivity reactions, oedema, Urticaria, respiratory difficulties, rhinitis, laryngospasm, facial swelling,
Ref :-   Book : Martindale    Page : 1927   Edition : 37,

►  Drug Interaction : Drug interaction of Sucralfate is with Cimetidine , Ranitidine , Digoxin , Olmesartan medoxomil , Ketoconazole , Levothyroxine, Phenytoin , Tetracycline , Quinidine , Theophylline , Warfarin ,
Ref :-   Book : Martindale    Page : 1928   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Sucralfate may interfere with the absorption of other drugs and it has been suggested that there should be an interval of 2 hours between giving sucralfate and other non-antacid medication. Some of the drugs reported to be affected by sucralfate include cimetidine, ranitidine, digoxin, fluoroquinolone antibacterials, ketoconazole, levothyroxine, phenytoin, tetracycline, quinidine, theophylline, and possibly warfarin.,
Ref :-   Book : Martindale    Page : 1928   Edition : 37,


►  Contraindication : renal impairment,
Ref :-   Book : Martindale    Page : 1927   Edition : 37,
  ►  Mechanism of Action :   Sucralfate is a cytoprotective drug that, under acid gastrointestinal conditions, forms an adherent complex with proteins which coats the gastric mucosa and is reported to have a special affinity for ulcer sites. It also inhibits the action of pepsin and adsorbs bile salts.,
Ref :-   Book : Martindale    Page : 1928   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- IRON with Dietary Substance is Drug Inhibitor,

  ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 1928   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA