Sugammadex is a Medicine belongs to Neuromuscular blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 1609   Edition : 37,

  ►   Brandname : Bridion

  ►  Strength : Injection with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 1609   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Neuromuscular blocker IV 2 4 mg/kg Injection

Ref :-  Book : Martindale    Page : 1577   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Neuromuscular blocker 2 Year 17 Year IV 2 mg/kg Injection

Ref :- Book : Martindale    Page : 1577   Edition : 38,
►  Side Effect : Dysgeusia,
Ref :-   Book : Goodman    Page : 268   Edition : 12,

►  Drug Interaction : Drug interaction of Sugammadex is with Toremifene, Flucloxacillin, Fusidic acid , Voglibose ,
Ref :-   Book : Martindale    Page : 1069   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Although no interaction studies have been carried out, theoretically rocuronium or vecuronium could be displaced from the complex formed with Sugammadex, resulting in re-occurrence of neuromuscular blockade Sugammadex may interfere with serum progesterone assays and some cogulation tests as activated partial thromboplastin time, prothrombin time and the international normalized ratio,
Ref :-   Book : Martindale    Page : 1609   Edition : 37,


►  Contraindication : renal impairment,
Ref :-   Book : Martindale    Page : 1609   Edition : 37,
  ►  Mechanism of Action :   Sugammadex Sodium is modified gamma cyclodextrin that is a selective relaxant binding agent used for the reversal of neuromuscular blockade induced by rocuronium or vecuronium,
Ref :-   Book : Martindale    Page : 1609   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1609   Edition : 37,


►    Plasma Half-life :
  Min value :-   1.8 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 1609   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,